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Title: Cannabis: An Overview of its Adverse Acute and Chronic Effects and its Implications.
Austin Authors: Ford, Talitha C;Hayley, Amie C ;Downey, Luke A;Parrott, Andrew C
Affiliation: Department of Psychology, School of Human and Health Sciences, Swansea University, Wales, United Kingdom
Centre for Human Psychopharmacology, Swinburne University, Melbourne, Australia
Institute for Breathing and Sleep, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 2017
Publication information: Current drug abuse reviews 2017; 10(1): 6-18
Abstract: In many communities, cannabis is perceived as a low-risk drug, leading to political lobbying to decriminalise its use. Acute and chronic cannabis use has been shown to be harmful to several aspects of psychological and physical health, such as mood states, psychiatric outcomes, neurocognition, driving and general health. Furthermore, cannabis is highly addictive, and the adverse effects of withdrawal can lead to regular use. These in turn have adverse implications for public safety and health expenditure. Although the cannabinoid cannabidiol (CBD) has been shown to have positive health outcomes with its antioxidant, anticonvulsant, anti-inflammatory and neuroprotective properties, high-potency cannabis is particularly damaging due to its high tetrahydrocannabinol (THC), low CDB concentration. It is this high-potency substance that is readily available recreationally. While pharmaceutical initiatives continue to investigate the medical benefits of CDB, "medicinal cannabis" still contains damaging levels of THC. Altogether, we argue there is insufficient evidence to support the safety of cannabis and its subsequent legalisation for recreational use. Furthermore, its use for medicinal purposes should be done with care. We argue that the public conversation for the legalisation of cannabis must include scientific evidence for its adverse effects.
DOI: 10.2174/1874473710666170712113042
PubMed URL: 28707583
Type: Journal Article
Subjects: Cannabis
Appears in Collections:Journal articles

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