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dc.contributor.authorHoward, Louise Michele-
dc.contributor.authorRyan, Elizabeth G-
dc.contributor.authorTrevillion, Kylee-
dc.contributor.authorAnderson, Fraser-
dc.contributor.authorBick, Debra-
dc.contributor.authorBye, Amanda-
dc.contributor.authorByford, Sarah-
dc.contributor.authorO'Connor, Sheila-
dc.contributor.authorSands, Polly-
dc.contributor.authorDemilew, Jill-
dc.contributor.authorMilgrom, Jeannette-
dc.contributor.authorPickles, Andrew-
dc.identifier.citationThe British journal of psychiatry 2018; 212(1): 50-56-
dc.description.abstractThere is limited evidence on the prevalence and identification of antenatal mental disorders. Aims To investigate the prevalence of mental disorders in early pregnancy and the diagnostic accuracy of depression-screening (Whooley) questions compared with the Edinburgh Postnatal Depression Scale (EPDS), against the Structured Clinical Interview DSM-IV-TR. Cross-sectional survey of women responding to Whooley questions asked at their first antenatal appointment. Women responding positively and a random sample of women responding negatively were invited to participate. Population prevalence was 27% (95% CI 22-32): 11% (95% CI 8-14) depression; 15% (95% CI 11-19) anxiety disorders; 2% (95% CI 1-4) obsessive-compulsive disorder; 0.8% (95% CI 0-1) post-traumatic stress disorder; 2% (95% CI 0.4-3) eating disorders; 0.3% (95% CI 0.1-1) bipolar disorder I, 0.3% (95% CI 0.1-1%) bipolar disorder II; 0.7% (95% CI 0-1) borderline personality disorder. For identification of depression, likelihood ratios were 8.2 (Whooley) and 9.8 (EPDS). Diagnostic accuracy was similar in identifying any disorder (likelihood ratios 5.8 and 6). Endorsement of Whooley questions in pregnancy indicates the need for a clinical assessment of diagnosis and could be implemented when maternity professionals have been appropriately trained on how to ask the questions sensitively, in settings where a clear referral and care pathway is available. Declaration of interest L.M.H. chaired the National Institute for Health and Care Excellence CG192 guidelines development group on antenatal and postnatal mental health in 2012-2014.-
dc.titleAccuracy of the Whooley questions and the Edinburgh Postnatal Depression Scale in identifying depression and other mental disorders in early pregnancy.-
dc.typeJournal Article-
dc.identifier.journaltitleThe British journal of psychiatry : the journal of mental science-
dc.identifier.affiliationSection of Women's Mental Health,Institute of Psychiatry, Psychology and Neuroscience, King's College London, London-
dc.identifier.affiliationSouth London and Maudsley NHS Foundation Trust, London-
dc.identifier.affiliationBiostatistics and Health Informatics Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London-
dc.identifier.affiliationWomen's Health Academic Centre, King's College London, London-
dc.identifier.affiliationFlorence Nightingale Faculty of Nursing and Midwifery, King's College London, London-
dc.identifier.affiliationKing's Health Economics,Institute of Psychiatry, Psychology and Neuroscience, King's College London, London-
dc.identifier.affiliationWomen's Health, King's College Hospital NHS Foundation Trust, London-
dc.identifier.affiliationParent-Infant Research Institute, Austin Health, Heidelberg, Victoria, Australia-
dc.identifier.affiliationMelbourne School of Psychological Sciences, University of Melbourne, Australia-
dc.type.austinJournal Article-, Jeannette
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
item.cerifentitytypePublications- Research Institute- and Health Psychology-
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