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dc.contributor.authorTu, Yan-
dc.contributor.authorJohnstone, Cameron N-
dc.contributor.authorStewart, Alastair G-
dc.identifier.citationPharmacological research 2017; 119: 278-288-
dc.description.abstractAnnexin A1 is a multifunctional protein characterised by its actions in modulating the innate and adaptive immune response. Accumulating evidence of altered annexin A1 expression in many human tumours raises interest in its functional role in cancer biology. In breast cancer, altered annexin A1 expression levels suggest a potential influence on tumorigenic and metastatic processes. However, reports of conflicting results reveal a relationship that is much more complex than first conceptualised. In this review, we explore the diverse actions of annexin A1 on breast tumour cells and various host cell types, including stromal immune and structural cells, particularly in the context of cancer immunoediting.-
dc.subjectAnnexin A1-
dc.subjectBreast cancer-
dc.subjectCancer immunoediting-
dc.subjectTumour microenvironment-
dc.subjectTumour stroma-
dc.titleAnnexin A1 influences in breast cancer: Controversies on contributions to tumour, host and immunoediting processes.-
dc.typeJournal Article-
dc.identifier.journaltitlePharmacological research-
dc.identifier.affiliationDepartment of Pharmacology and Therapeutics, The University of Melbourne, Parkville, Melbourne, Australia-
dc.identifier.affiliationCancer & Inflammation Laboratory, Olivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia-
dc.type.austinJournal Article-
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.cerifentitytypePublications- Newton-John Cancer Research Institute-
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