Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/16702
Full metadata record
DC FieldValueLanguage
dc.contributor.authorChisanga, David-
dc.contributor.authorKeerthikumar, Shivakumar-
dc.contributor.authorPathan, Mohashin-
dc.contributor.authorAriyaratne, Dinuka-
dc.contributor.authorKalra, Hina-
dc.contributor.authorBoukouris, Stephanie-
dc.contributor.authorAbraham Mathew, Nidhi-
dc.contributor.authorAl Saffar, Haidar-
dc.contributor.authorGangoda, Lahiru-
dc.contributor.authorAng, Ching-Seng-
dc.contributor.authorSieber, Oliver M-
dc.contributor.authorMariadason, John M-
dc.contributor.authorDasgupta, Ramanuj-
dc.contributor.authorChilamkurti, Naveen-
dc.contributor.authorMathivanan, Suresh-
dc.date2015-10-22-
dc.date.accessioned2017-07-04T04:58:30Z-
dc.date.available2017-07-04T04:58:30Z-
dc.date.issued2016-01-
dc.identifier.citationNucleic Acids Research 2016; 44(D1): D969-974en
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/16702-
dc.description.abstractIn order to advance our understanding of colorectal cancer (CRC) development and progression, biomedical researchers have generated large amounts of OMICS data from CRC patient samples and representative cell lines. However, these data are deposited in various repositories or in supplementary tables. A database which integrates data from heterogeneous resources and enables analysis of the multidimensional data sets, specifically pertaining to CRC is currently lacking. Here, we have developed Colorectal Cancer Atlas (http://www.colonatlas.org), an integrated web-based resource that catalogues the genomic and proteomic annotations identified in CRC tissues and cell lines. The data catalogued to-date include sequence variations as well as quantitative and non-quantitative protein expression data. The database enables the analysis of these data in the context of signaling pathways, protein-protein interactions, Gene Ontology terms, protein domains and post-translational modifications. Currently, Colorectal Cancer Atlas contains data for >13 711 CRC tissues, >165 CRC cell lines, 62 251 protein identifications, >8.3 million MS/MS spectra, >18 410 genes with sequence variations (404 278 entries) and 351 pathways with sequence variants. Overall, Colorectal Cancer Atlas has been designed to serve as a central resource to facilitate research in CRC.en
dc.subjectColorectal Neoplasmsen
dc.subjectDatabases, Geneticen
dc.subjectGenomicsen
dc.subjectProteomicsen
dc.titleColorectal cancer atlas: an integrative resource for genomic and proteomic annotations from colorectal cancer cell lines and tissuesen
dc.typeJournal Articleen
dc.identifier.journaltitleNucleic Acids Researchen
dc.identifier.affiliationAustin Health, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationDepartment of Computer Science and Information Technology, La Trobe University, Bundoora, Victoria, Australiaen
dc.identifier.affiliationThe Bio21 Molecular Science and Biotechnology Institute, University of Melbourne, Parkville, Victoria, Australiaen
dc.identifier.affiliationWalter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australiaen
dc.identifier.affiliationFaculty of Medicine, Dentistry and Health Sciences, Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australiaen
dc.identifier.affiliationOlivia Newton John Cancer Research Institute, Melbourne, Victoria, Australiaen
dc.identifier.affiliationLudwig Institute for Cancer Research, Melbourne-Austin Branch, Victoria, Australiaen
dc.identifier.affiliationDepartment of Biochemistry and Genetics, La Trobe Institute for Molecular Science, La Trobe University, Melbourne, Victoria, Australiaen
dc.identifier.pubmedurihttps://pubmed.ncbi.nlm.nih.gov/26496946en
dc.identifier.doi10.1093/nar/gkv1097en
dc.type.contentTexten
dc.type.austinJournal Articleen_US
local.name.researcherMariadason, John M
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
crisitem.author.deptOlivia Newton-John Cancer Research Institute-
Appears in Collections:Journal articles
Show simple item record

Page view(s)

6
checked on Feb 21, 2024

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.