Immediate adjuvant radiation therapy following radical prostatectomy should not be advised for men with extraprostatic extension who have negative surgical margins

2016-02

Walsh, Patrick C

Lawrentschuk, Nathan

Patient Selection

Prostatic Neoplasms

Journal Article

0000-0001-8553-5618

10.1016/j.eururo.2015.09.045

Although three large randomized prospective clinical trials have demonstrated that postoperative radiotherapy in patients with adverse pathological features reduces prostate-specific antigen recurrence and may decrease clinical failure, this approach has not gained widespread acceptance, likely because the data strongly support such an approach only in men with Gleason ≥7 with positive surgical margins.

link

European Urology 2016; 69(2): 191-192

European Urology