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Title: Immediate adjuvant radiation therapy following radical prostatectomy should not be advised for men with extraprostatic extension who have negative surgical margins
Austin Authors: Walsh, Patrick C;Lawrentschuk, Nathan
Affiliation: James Buchanan Brady Urological Institute, Johns Hopkins Medical Institutions, Baltimore, MD, USA
Department of Surgery, University of Melbourne, Melbourne, Victoria, Australia
Olivia Newton-John Cancer Research Institute, Austin Health, Heidelberg, Victoria, Australia
Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia
Issue Date: Feb-2016 2015-10-23
Publication information: European Urology 2016; 69(2): 191-192
Abstract: Although three large randomized prospective clinical trials have demonstrated that postoperative radiotherapy in patients with adverse pathological features reduces prostate-specific antigen recurrence and may decrease clinical failure, this approach has not gained widespread acceptance, likely because the data strongly support such an approach only in men with Gleason ≥7 with positive surgical margins.
DOI: 10.1016/j.eururo.2015.09.045
ORCID: 0000-0001-8553-5618
PubMed URL:
Type: Journal Article
Subjects: Patient Selection
Prostatic Neoplasms
Appears in Collections:Journal articles

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