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dc.contributor.authorFoo, Chuan T-
dc.contributor.authorBurrell, Louise Men
dc.contributor.authorJohnson, Douglas F-
dc.identifier.citationOxford Medical Case Reports 2016; 8: 159-162en_US
dc.description.abstractA 67-year old previously well male presented with a 1 week history of confusion on a background of 3 weeks of headache. Past history included two superficial melanomas excised 5 years ago. Treatment for meningoencephalitis was commenced based on lumbar puncture (LP) and non-contrast brain magnetic resonance imaging (MRI) results. Lack of a clinical response to antibiotics resulted in a second LP and contrast brain MRI which demonstrated hydrocephalus and leptomeningeal disease. Ongoing deterioration led to a whole-body computed tomographic and spinal MRI that showed widespread metastatic disease and extensive leptomeningeal involvement of the spinal cord. The diagnosis of metastatic melanoma with carcinomatous meningitis was made based on cytological analysis of cerebrospinal fluid. He died 2 weeks later in a palliative care facility. This case illustrates that the diagnosis of carcinomatous meningitis can be difficult to make as the heterogeneous nature of its presentation often delays the diagnosis.en_US
dc.subjectCentral nervous system canceren_US
dc.subjectLeptomeningeal diseaseen_US
dc.subjectSkin canceren_US
dc.titleAn unusual presentation of carcinomatous meningitisen_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleOxford Medical Case Reportsen_US
dc.identifier.affiliationDepartment of Medicine, Austin Health, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationDepartment of Medicine, The University of Melbourne, Heidelberg, Victoria, Australiaen_US
dc.identifier.affiliationAustin Health, Heidelberg, Victoria, Australiaen_US
dc.type.austinJournal Articleen_US
item.openairetypeJournal Article-
item.fulltextWith Fulltext-
item.cerifentitytypePublications- Medicine- (University of Melbourne)-
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