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dc.contributor.authorFowler, K Sen
dc.contributor.authorSaling, Michael Men
dc.contributor.authorConway, Elizabeth Len
dc.contributor.authorSemple, J Men
dc.contributor.authorLouis, William Jen
dc.identifier.citationJournal of the International Neuropsychological Society : Jins; 3(2): 139-46en
dc.description.abstractThis longitudinal study examines the sensitivity of 2 computerized neuropsychological tests, delayed matching to sample and paired associate learning, to early dementia of the Alzheimer type (DAT). Normal controls, patients in the early stages of DAT, and individuals with questionable dementia (QD) were studied. At 6 and 12 months after initial presentation, almost half of the QD group exhibited lower scores on the computerized subtests, maintaining their scores on standard testing. Over the same period NC subjects maintained their performance levels, while DAT patients continued to deteriorate. Linear discriminant function analyses of the computerized subtests at 6 and 12 months correctly classified 100% of the early DAT patients. Eighty-four and 79 percent of normal controls were correctly classified at 6 and 12 months respectively. Further development of these subtests for the detection of early dementia and the documentation of ongoing change in DAT is warranted. The findings are discussed in terms of the special sensitivity of these tests to the neuropathology of Alzheimer's Disease.en
dc.subject.otherAlzheimer Disease.classification.diagnosis.psychologyen
dc.subject.otherDiagnosis, Computer-Assisted.statistics & numerical dataen
dc.subject.otherDiscrimination Learningen
dc.subject.otherLongitudinal Studiesen
dc.subject.otherMental Recallen
dc.subject.otherMiddle Ageden
dc.subject.otherNeuropsychological Tests.statistics & numerical dataen
dc.subject.otherPaired-Associate Learningen
dc.subject.otherPattern Recognition, Visualen
dc.subject.otherProspective Studiesen
dc.subject.otherSensitivity and Specificityen
dc.titleComputerized neuropsychological tests in the early detection of dementia: prospective findings.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of the International Neuropsychological Society : JINSen
dc.identifier.affiliationDepartment of Clinical Pharmacology and Therapeutics, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.type.austinJournal Articleen
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.cerifentitytypePublications- Neuropsychology- Florey Institute of Neuroscience and Mental Health- Pharmacology and Therapeutics-
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