Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/13486
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dc.contributor.authorThurlow, P Jen
dc.contributor.authorDoolan, Laurieen
dc.contributor.authorSharp, Ren
dc.contributor.authorSullivan, Men
dc.contributor.authorSmith, Ben
dc.contributor.authorAndersen, L Wen
dc.date.accessioned2015-05-16T03:21:09Z
dc.date.available2015-05-16T03:21:09Z
dc.date.issued1996-01-01en
dc.identifier.citationPerfusion; 11(1): 29-37en
dc.identifier.govdoc8904324en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/13486en
dc.description.abstractA total of 14 patients with ischaemic heart disease undergoing coronary artery bypass grafts were studied for the effect of AV6 control filter and LG6 neutrophil filter, used in the extracorporeal circulation, on different laboratory parameters. There was no statistical difference between the effects of AV6 and LG6 filters on total white cells, neutrophils, monocytes, lymphocytes, platelets or haemoglobin. The expression of neutrophil activation antigens identified with a panel of monoclonal antibodies demonstrated that for the LG6 filter the leucocyte tyrosine phosphate CD45Ro fell during the procedure, whilst there were no significant changes in any of the other neutrophil antigens. The AV6 filter did not significantly diminish the expression of any of the neutrophil antigens. An indirect measure of superoxide production using Dihydrorhodamine 123 identified that the more activated cells appeared to be depleted across the LG6 filter which was not evident with the AV6 filter. These studies indicate that the LG6 is not capable of significantly depleting the neutrophil load generated during extracorporeal circulation but may be capable of selectively removing the more activated forms.en
dc.language.isoenen
dc.subject.otherAgeden
dc.subject.otherAntigens, CD.analysisen
dc.subject.otherCardiopulmonary Bypassen
dc.subject.otherCoronary Artery Bypassen
dc.subject.otherFiltrationen
dc.subject.otherHumansen
dc.subject.otherLeukocyte Counten
dc.subject.otherMiddle Ageden
dc.subject.otherNeutrophil Activationen
dc.subject.otherNeutrophils.physiologyen
dc.titleLaboratory studies of the effect of Pall extracorporeal leucocyte filters LG6 and AV6 on patients undergoing coronary bypass grafts.en
dc.typeJournal Articleen
dc.identifier.journaltitlePerfusionen
dc.identifier.affiliationDepartments of Haematology and Anaesthesia, Austin Hospital, Heidelberg, Australiaen
dc.description.pages29-37en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/8904324en
dc.type.austinJournal Articleen
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
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