Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/13019
Title: The effect of incisional infiltration of bupivacaine upon pain and respiratory function following open cholecystectomy.
Austin Authors: Russell, W C;Ramsay, A H;Fletcher, D R
Affiliation: University of Melbourne, Department of Surgery, Austin Hospital, Victoria, Australia
Issue Date: 1-Oct-1993
Publication information: Australian and New Zealand Journal of Surgery; 63(10): 756-9
Abstract: A controlled, prospective, double-blind trial of wound infiltration with bupivacaine in elective open cholecystectomy was performed to determine if this was an effective method of pain relief and reduced respiratory complications. Additionally, dextran was added to the bupivacaine in an attempt to prolong the effect. The solutions used were, bupivacaine alone 0.25% (n = 14), bupivacaine 0.25% with dextran 70 (n = 16) and saline (n = 16) as a control. To determine the effect of each solution, the subjects were assessed for pain perception and respiratory function before and after surgery. Pain was assessed using a visual analogue scale and narcotic usage, and respiratory function was assessed by spirometry, chest X-rays and arterial blood gases. The study did not demonstrate any objective improvement in either pain relief or respiratory function. This may reflect inadequate infiltration by the surgeons in the study or that infiltration should have been performed prior to incision.
Gov't Doc #: 7506020
URI: http://ahro.austin.org.au/austinjspui/handle/1/13019
URL: https://pubmed.ncbi.nlm.nih.gov/7506020
Type: Journal Article
Subjects: Adult
Bupivacaine.administration & dosage.pharmacology
Cholecystectomy.methods
Dextrans.administration & dosage.pharmacology
Double-Blind Method
Elective Surgical Procedures
Female
Forced Expiratory Volume.physiology
Humans
Injections, Intraperitoneal
Male
Middle Aged
Oxygen.blood
Pain Measurement
Pain, Postoperative.prevention & control
Prospective Studies
Pulmonary Atelectasis.physiopathology.radiography
Respiration.drug effects
Time Factors
Vital Capacity.physiology
Appears in Collections:Journal articles

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