Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/13018
Full metadata record
DC FieldValueLanguage
dc.contributor.authorXing, Pei Xiangen
dc.contributor.authorApostolopoulos, Ven
dc.contributor.authorPrenzoska, Jen
dc.contributor.authorDevine, P Len
dc.contributor.authorMcKenzie, Ian F Cen
dc.date.accessioned2015-05-16T02:47:29Z
dc.date.available2015-05-16T02:47:29Z
dc.date.issued1993-12-01en
dc.identifier.citationScandinavian Journal of Immunology; 38(6): 591-2en
dc.identifier.govdoc7504828en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/13018en
dc.description.abstractMultiple genes coding for human mucins have been identified (MUC 1-5) and here monoclonal antibodies (MoAb) to a gastrointestinal mucin--MUC2 are examined. The antibodies were made to a synthetic peptide representing a single repeat in the core protein of the variable number of tandem repeat region. Using the six-mer overlapping peptides synthesized on polyethylene pins, different binding sites were detected by five anti-MUC 2 MoAbs. These contained amino acids: STTT, PTT, GTQTP, TPTP and PTTT (one antibody), and TPTPT. The repeat region of MUC2 essentially is hydrophobic, but contain useful immunogenic sites. This information will be useful for studying the structure and function of MUC2.en
dc.language.isoenen
dc.subject.otherAmino Acid Sequenceen
dc.subject.otherAntibodies, Monoclonal.immunologyen
dc.subject.otherBinding Sites, Antibodyen
dc.subject.otherDigestive System.immunologyen
dc.subject.otherEpitopesen
dc.subject.otherHumansen
dc.subject.otherMolecular Sequence Dataen
dc.subject.otherMucin-2en
dc.subject.otherMucins.immunologyen
dc.subject.otherNeoplasm Proteins.immunologyen
dc.subject.otherOligopeptides.chemistryen
dc.subject.otherStructure-Activity Relationshipen
dc.titlePeptide binding sites recognized by anti-mucin (MUC2) monoclonal antibodies.en
dc.typeJournal Articleen
dc.identifier.journaltitleScandinavian journal of immunologyen
dc.identifier.affiliationAustin Research Institute, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pages591-2en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/7504828en
dc.type.austinJournal Articleen
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.cerifentitytypePublications-
Appears in Collections:Journal articles
Show simple item record

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.