Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12956
Full metadata record
DC FieldValueLanguage
dc.contributor.authorAllen, A Men
dc.contributor.authorMcKinley, M Jen
dc.contributor.authorMendelsohn, Frederick AOen
dc.date.accessioned2015-05-16T02:43:20Z
dc.date.available2015-05-16T02:43:20Z
dc.date.issued1988-02-01en
dc.identifier.citationClinical and Experimental Pharmacology & Physiology; 15(2): 137-45en
dc.identifier.govdoc3271605en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/12956en
dc.description.abstract1. The distribution of angiotensin II (AII) receptor binding sites in the hypothalamus of rat, rabbit, sheep and human was determined by in vitro autoradiography using 125I-[Sar1,Ile8]-AII as radioligand. 2. High receptor binding levels were observed in the continuum of tissue comprising the anterior wall of the third ventricle, including the subfornical organ, the median pre-optic nucleus and the organum vasculosum of the lamina terminalis. 3. High levels of binding sites were also found in the paraventricular and supra-optic nuclei, the median eminence and the arcuate nucleus. 4. These findings demonstrate sites in the hypothalamus of rat, rabbit, sheep and human where AII could exert its known actions on fluid and electrolyte balance, pituitary hormone release and cardiovascular function.en
dc.language.isoenen
dc.subject.otherAgeden
dc.subject.otherAnimalsen
dc.subject.otherAutoradiographyen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherHypothalamus.anatomy & histology.metabolismen
dc.subject.otherIn Vitro Techniquesen
dc.subject.otherIodine Radioisotopes.diagnostic useen
dc.subject.otherMaleen
dc.subject.otherRabbitsen
dc.subject.otherRatsen
dc.subject.otherRats, Inbred Strainsen
dc.subject.otherReceptors, Angiotensin.drug effects.metabolismen
dc.subject.otherSaralasin.pharmacologyen
dc.subject.otherSheepen
dc.subject.otherSpecies Specificityen
dc.titleComparative neuroanatomy of angiotensin II receptor localization in the mammalian hypothalamus.en
dc.typeJournal Articleen
dc.identifier.journaltitleClinical and Experimental Pharmacology & Physiologyen
dc.identifier.affiliationUniversity of Melbourne Department of Medicine, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pages137-45en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/3271605en
dc.type.austinJournal Articleen
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
Appears in Collections:Journal articles
Show simple item record

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.