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https://ahro.austin.org.au/austinjspui/handle/1/12902| Title: | Platelet monoamine oxidase activity in patients with Huntington's disease. | Austin Authors: | Norman, Trevor R ;Chiu, E;French, M A | Affiliation: | Department of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australia | Issue Date: | 1-Jun-1987 | Publication information: | Clinical and Experimental Pharmacology & Physiology; 14(6): 547-50 | Abstract: | 1. Platelet monoamine oxidase (MAO) activity was investigated in 30 patients with Huntington's disease and compared with the activity in a control group. 2. Significantly elevated activity was found in the patients (P less than 0.05; t-test) when same sex contrasts were carried out to account for the well known influence of sex on MAO activity. 3. The mean MAO activity in male patients was 23.5 +/- 6.0 nmol/mg protein per h and female patients was 29.5 +/- 8.9 nmol/mg protein per h using tyramine as the substrate. 4. The possible influence of environmental factors on the results is discussed. | Gov't Doc #: | 2960476 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/12902 | Journal: | Clinical and Experimental Pharmacology & Physiology | URL: | https://pubmed.ncbi.nlm.nih.gov/2960476 | Type: | Journal Article | Subjects: | Adolescent Adult Blood Platelets.enzymology Female Humans Huntington Disease.enzymology Male Middle Aged Monoamine Oxidase.blood Smoking.metabolism |
| Appears in Collections: | Journal articles |
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