Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12901
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dc.contributor.authorHodsman, G Pen
dc.contributor.authorJackson, Ben
dc.contributor.authorDebrevi, L Men
dc.contributor.authorOgawa, Ken
dc.contributor.authorJohnston, Colin Ien
dc.date.accessioned2015-05-16T02:39:11Z
dc.date.available2015-05-16T02:39:11Z
dc.date.issued1987-03-01en
dc.identifier.citationClinical and Experimental Pharmacology & Physiology; 14(3): 247-51en
dc.identifier.govdoc2959420en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/12901en
dc.description.abstract1. Plasma concentration and atrial content of atrial natriuretic factor (ANF) were measured in rats with chronic renal failure induced by subtotal nephrectomy. 2. Plasma ANF was higher, and atrial ANF content lower in rats with renal failure when compared with sham-operated controls. 3. Plasma renin activity (PRA) and ANF were elevated at 1 week following subtotal nephrectomy. After 1 month plasma ANF had risen further, but PRA was suppressed to below control values. 4. Plasma ANF was also measured in six patients with chronic renal failure undergoing routine haemodialysis. 5. Elevated plasma ANF levels in patients with renal failure were lowered by haemodialysis, although extraction of ANF across the dialysis membrane was negligible. 6. Secretion of ANF is increased in chronic renal failure in man and the rat, possibly mediated by increased intravascular volume.en
dc.language.isoenen
dc.subject.otherAnimalsen
dc.subject.otherAtrial Natriuretic Factor.blooden
dc.subject.otherBody Weighten
dc.subject.otherCreatinine.blooden
dc.subject.otherHematocriten
dc.subject.otherHumansen
dc.subject.otherKidney Failure, Chronic.metabolismen
dc.subject.otherMaleen
dc.subject.otherNephrectomyen
dc.subject.otherRatsen
dc.subject.otherRats, Inbred Strainsen
dc.subject.otherRenal Dialysisen
dc.subject.otherRenin.blooden
dc.subject.otherRenin-Angiotensin Systemen
dc.titleAtrial natriuretic factor in chronic renal failure: studies in man and the rat.en
dc.typeJournal Articleen
dc.identifier.journaltitleClinical and Experimental Pharmacology & Physiologyen
dc.identifier.affiliationUniversity of Melbourne, Department of Medicine, Austin Hospital, Heidelberg, Victoria.en
dc.description.pages247-51en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/2959420en
dc.type.austinJournal Articleen
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeJournal Article-
item.grantfulltextnone-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
crisitem.author.deptGastroenterology and Hepatology-
Appears in Collections:Journal articles
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