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Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12900
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dc.contributor.authorNorman, Trevor Ren
dc.contributor.authorChiu, Een
dc.contributor.authorJames, R Hen
dc.contributor.authorGregory, M Sen
dc.date.accessioned2015-05-16T02:39:07Z
dc.date.available2015-05-16T02:39:07Z
dc.date.issued1987-05-16en
dc.identifier.citationEuropean Journal of Clinical Pharmacology; 32(6): 583-6en
dc.identifier.govdoc2958291en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/12900en
dc.description.abstractThe pharmacokinetic properties of a single oral dose of 100 mg of tiapride were studied in six patients with Huntington's disease. The results for five patients were consistent with a two compartment open model. Peak plasma concentrations were observed within 2 h following drug administration with a mean value of 0.92 micrograms/ml being recorded. The drug was rapidly eliminated as unmetabolised tiapride in the urine, 51% of the dose was recovered in 24 h. The plasma elimination half-life was 5.3 h and the average apparent plasma clearance was 16.6 l/h.en
dc.language.isoenen
dc.subject.otherAdministration, Oralen
dc.subject.otherAdulten
dc.subject.otherAgeden
dc.subject.otherBenzamides.pharmacokineticsen
dc.subject.otherFemaleen
dc.subject.otherHalf-Lifeen
dc.subject.otherHumansen
dc.subject.otherHuntington Disease.metabolismen
dc.subject.otherKidney.metabolismen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherTiapamil Hydrochloride.pharmacokineticsen
dc.titleSingle oral dose pharmacokinetics of tiapride in patients with Huntington's disease.en
dc.typeJournal Articleen
dc.identifier.journaltitleEuropean journal of clinical pharmacologyen
dc.identifier.affiliationDepartment of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pages583-6en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/2958291en
dc.type.austinJournal Articleen
local.name.researcherNorman, Trevor R
item.openairetypeJournal Article-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en-
crisitem.author.deptPsychiatry (University of Melbourne)-
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