Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12895
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dc.contributor.authorMcIntyre, I Men
dc.contributor.authorNorman, Trevor Ren
dc.contributor.authorBurrows, Graham Den
dc.contributor.authorArmstrong, S Men
dc.date.accessioned2015-05-16T02:38:47Z
dc.date.available2015-05-16T02:38:47Z
dc.date.issued1989-05-16en
dc.identifier.citationJournal of Pineal Research; 6(2): 149-56en
dc.identifier.govdoc2915324en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/12895en
dc.description.abstractFive intensities of artificial light were examined for the effect on nocturnal melatonin concentrations. Maximum suppression of melatonin following 1 hr of light at midnight was 71%, 67%, 44%, 38%, and 16% with intensities of 3,000, 1,000, 500, 350, and 200 lux (lx), respectively. In contrast to some previous reports, light of 1,000 lx intensity was sufficient to suppress melatonin to near daytime levels, and intensities down to 350 lx were shown to significantly suppress nocturnal melatonin levels below prelight values. On the basis of these data, it is suggested that when examining the melatonin sensitivity of patient groups (such as bipolar affective disorders) to artificial light, an appropriate light intensity should be established in each laboratory. Light of less intensity (e.g., 200-350 lx) may be more suitable to dichotomize patient groups from control subjects.en
dc.language.isoenen
dc.subject.otherAdulten
dc.subject.otherBipolar Disorder.physiopathologyen
dc.subject.otherDose-Response Relationship, Radiationen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherLighten
dc.subject.otherLightingen
dc.subject.otherMaleen
dc.subject.otherMelatonin.blooden
dc.subject.otherReference Valuesen
dc.titleHuman melatonin suppression by light is intensity dependent.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of pineal researchen
dc.identifier.affiliationDepartment of Psychiatry, University of Melbourne, Austin Hospital, Heidelberg, Australiaen
dc.description.pages149-56en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/2915324en
dc.type.austinJournal Articleen
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptPsychiatry (University of Melbourne)-
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