Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12840
Title: Effects of sodium restriction on cardiac 3,4-dihydroxyphenylethylene glycol and catecholamine levels in rats.
Austin Authors: Howes, L G;Hodsman, G P
Affiliation: University of Melbourne, Department of Medicine, Austin Hospital, Heidelberg, Victoria, Australia
Issue Date: 1-Aug-1989
Publication information: Clinical and Experimental Pharmacology & Physiology; 16(8): 671-4
Abstract: 1. The effects of low or high sodium intake for 4 weeks on cardiac catecholamines and 3,4-dihydroxyphenylethylene glycol (DHPG) levels were studied in adult female Wistar rats. 2. Rats receiving the low sodium diet had significantly higher plasma renin activity than rats receiving the high sodium diet. 3. Dopamine concentrations in both the right and left ventricle were significantly higher in the low salt compared with the high salt rats, but noradrenaline, adrenaline and DHPG levels did not differ significantly between the two groups. 4. These data do not support previous reports that sodium restriction reduces cardiac noradrenaline release, but suggest that alterations in sodium intake may influence cardiac noradrenaline metabolism.
Gov't Doc #: 2791336
URI: http://ahro.austin.org.au/austinjspui/handle/1/12840
URL: https://pubmed.ncbi.nlm.nih.gov/2791336
Type: Journal Article
Subjects: Animals
Catecholamines.metabolism
Diet, Sodium-Restricted
Dopamine.metabolism
Epinephrine.metabolism
Female
Glycols.metabolism
Heart.drug effects
Methoxyhydroxyphenylglycol.metabolism
Myocardium.metabolism
Norepinephrine.metabolism
Organ Size
Radioimmunoassay
Rats
Rats, Inbred Strains
Appears in Collections:Journal articles

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