Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/12840
Title: | Effects of sodium restriction on cardiac 3,4-dihydroxyphenylethylene glycol and catecholamine levels in rats. | Austin Authors: | Howes, L G;Hodsman, G P | Affiliation: | University of Melbourne, Department of Medicine, Austin Hospital, Heidelberg, Victoria, Australia | Issue Date: | 1-Aug-1989 | Publication information: | Clinical and Experimental Pharmacology & Physiology; 16(8): 671-4 | Abstract: | 1. The effects of low or high sodium intake for 4 weeks on cardiac catecholamines and 3,4-dihydroxyphenylethylene glycol (DHPG) levels were studied in adult female Wistar rats. 2. Rats receiving the low sodium diet had significantly higher plasma renin activity than rats receiving the high sodium diet. 3. Dopamine concentrations in both the right and left ventricle were significantly higher in the low salt compared with the high salt rats, but noradrenaline, adrenaline and DHPG levels did not differ significantly between the two groups. 4. These data do not support previous reports that sodium restriction reduces cardiac noradrenaline release, but suggest that alterations in sodium intake may influence cardiac noradrenaline metabolism. | Gov't Doc #: | 2791336 | URI: | http://ahro.austin.org.au/austinjspui/handle/1/12840 | Journal: | Clinical and Experimental Pharmacology & Physiology | URL: | https://pubmed.ncbi.nlm.nih.gov/2791336 | Type: | Journal Article | Subjects: | Animals Catecholamines.metabolism Diet, Sodium-Restricted Dopamine.metabolism Epinephrine.metabolism Female Glycols.metabolism Heart.drug effects Methoxyhydroxyphenylglycol.metabolism Myocardium.metabolism Norepinephrine.metabolism Organ Size Radioimmunoassay Rats Rats, Inbred Strains |
Appears in Collections: | Journal articles |
Show full item record
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.