Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12838
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dc.contributor.authorJohnson, Hen
dc.contributor.authorKourtis, Sen
dc.contributor.authorWaters, Jen
dc.contributor.authorDrummer, Olaf Hen
dc.date.accessioned2015-05-16T02:35:04Z
dc.date.available2015-05-16T02:35:04Z
dc.date.issued1989-05-06en
dc.identifier.citationPeptides; 10(3): 489-92en
dc.identifier.govdoc2780412en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/12838en
dc.description.abstractA specific radioimmunoassay for the angiotensin-derived peptide [des-Leu10]-angiotensin I (AI-dL) is described. Antisera obtained from rabbits injected with immunogen prepared by coupling bovine beta-thyroglobulin to the peptide with carbodiimide were specific to this peptide and did not recognise related angiotensin peptides such as AI, AII, AIII, nor did they recognise other peptides such as bradykinin, substance P, bombesin or dynorphin(1-8). Immunoreactive AI-dL was detected for the first time in the plasma of rats and humans following purification by HPLC at concentrations of 78 and 40 pg/ml, respectively. Concentrations of AI-dL are increased following chronic administration of captopril to rats.en
dc.language.isoenen
dc.subject.otherAngiotensin I.analogs & derivatives.blood.isolation & purificationen
dc.subject.otherAnimalsen
dc.subject.otherChromatography, High Pressure Liquiden
dc.subject.otherCross Reactionsen
dc.subject.otherHumansen
dc.subject.otherImmune Seraen
dc.subject.otherRabbits.immunologyen
dc.subject.otherRadioimmunoassay.methodsen
dc.subject.otherRatsen
dc.titleRadioimmunoassay for immunoreactive [des-Leu10]-angiotensin I.en
dc.typeJournal Articleen
dc.identifier.journaltitlePeptidesen
dc.identifier.affiliationUniversity of Melbourne, Clinical Pharmacology and Therapeutics Unit, Austin Hospital, Heidelberg, Australiaen
dc.description.pages489-92en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/2780412en
dc.type.austinJournal Articleen
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.cerifentitytypePublications-
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