Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12640
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dc.contributor.authorLewis, S Jen
dc.contributor.authorDunlop, Men
dc.contributor.authorJarrott, Ben
dc.date.accessioned2015-05-16T02:21:58Z
dc.date.available2015-05-16T02:21:58Z
dc.date.issued1989-05-01en
dc.identifier.citationThe Journal of Pharmacy and Pharmacology; 41(5): 353-5en
dc.identifier.govdoc2569528en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/12640en
dc.description.abstractThe concentrations of glucose were elevated whereas those of insulin were decreased in the sera of normotensive Wistar-Kyoto (WKY) and spontaneously hypertensive (SH) rats on day 10 of a continuous subcutaneous infusion of clonidine (10 micrograms kg-1 h-1 for 10 days). Fifteen to 18 h after cessation of infusion, the glucose levels of both strains had fallen to below those of the respective controls whereas the insulin levels remained suppressed. As such the hypoglycaemia may be related to the general increase in metabolic requirements associated with the post-infusion 'withdrawal syndrome'.en
dc.language.isoenen
dc.subject.otherAnimalsen
dc.subject.otherBlood Glucose.metabolismen
dc.subject.otherBody Temperature.drug effectsen
dc.subject.otherBody Weighten
dc.subject.otherClonidine.administration & dosage.pharmacologyen
dc.subject.otherFemaleen
dc.subject.otherInfusions, Intravenousen
dc.subject.otherInsulin.blooden
dc.subject.otherRatsen
dc.subject.otherRats, Inbred SHRen
dc.subject.otherRats, Inbred WKYen
dc.titleSerum glucose and insulin levels in normotensive (WKY) and spontaneously hypertensive (SH) rats during and after the cessation of continuous (10 day) clonidine infusion.en
dc.typeJournal Articleen
dc.identifier.journaltitleThe Journal of pharmacy and pharmacologyen
dc.identifier.affiliationUniversity of Melbourne, Clinical Pharmacology and Therapeutics Unit, Austin Hospital, Heidelberg, Victoria, Australiaen
dc.description.pages353-5en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/2569528en
dc.type.austinJournal Articleen
item.grantfulltextnone-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
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