Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12513
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dc.contributor.authorEastwood, Glenn Men
dc.contributor.authorSuzuki, Satoshien
dc.contributor.authorLluch, Cristinaen
dc.contributor.authorSchneider, Antoine Gen
dc.contributor.authorBellomo, Rinaldoen
dc.date.accessioned2015-05-16T02:13:14Z-
dc.date.available2015-05-16T02:13:14Z-
dc.date.issued2014-10-02en
dc.identifier.citationJournal of Critical Care 2014; 30(1): 138-44en
dc.identifier.govdoc25449882en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/12513en
dc.description.abstractResuscitated cardiac arrest (CA) patients typically receive therapeutic hypothermia, but arterial blood gases (ABGs) are often assessed after adjustment to 37°C (alpha-stat) instead of actual body temperature (pH-stat). We sought to compare alpha-stat and pH-stat assessment of PaO2 and PaCO2 in such patients.Using ABG data obtained during the first 24 hours of intensive care unit admission, we determined the impact of measured alpha vs calculated pH-stat on PaO2 and PaCO2 on patient classification and outcomes for CA patients.We assessed 1013 ABGs from 120 CA patients with a median age of patients 66 years (interquartile range, 50-76). Median alpha-stat PaO2 changed from 122 (95-156) to 107 (82-143) mm Hg with pH-stat and median PaCO2 from 39 (34-46) to 35 (30-41) mm Hg (both P < .001). Using the categories of hyperoxemia, normoxemia, and hypoxemia, pH-stat estimation of PaO2 reclassified approximately 20% of patients. Using the categories of hypercapnia, normocapnia, and hypocapnia, pH stat estimation of PaCO2 reclassified approximately 40% of patients. The mortality of patients in different PaO2 and PaCO2 categories was similar for pH-stat and alpha-stat.Using the pH-stat method, fewer resuscitated CA patients admitted to intensive care unit were classified as hyperoxemic or hypercapnic compared with alpha-stat. These findings suggest an impact of ABG assessment methodology on PaO2, PaCO2 , and patient classification but not on associated outcomes.en
dc.language.isoenen
dc.subject.otherArterial blood gasen
dc.subject.otherCardiac arresten
dc.subject.otherHyperoxemiaen
dc.subject.otherHypocapniaen
dc.subject.otherHypoxemiaen
dc.subject.otherIntensive careen
dc.subject.otherAdulten
dc.subject.otherAgeden
dc.subject.otherAnoxia.blood.complicationsen
dc.subject.otherArteriesen
dc.subject.otherBlood Gas Analysisen
dc.subject.otherBody Temperatureen
dc.subject.otherFemaleen
dc.subject.otherHeart Arrest.blood.mortalityen
dc.subject.otherHumansen
dc.subject.otherHypercapnia.blood.diagnosisen
dc.subject.otherHyperoxia.blood.diagnosisen
dc.subject.otherHypothermia, Induceden
dc.subject.otherIntensive Care Unitsen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherPilot Projectsen
dc.subject.otherRetrospective Studiesen
dc.titleA pilot assessment of alpha-stat vs pH-stat arterial blood gas analysis after cardiac arrest.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of Critical Careen
dc.identifier.affiliationDepartment of Intensive Care, Austin Hospital, Victoria, Melbourne, Australiaen
dc.identifier.affiliationDepartment of Epidemiology and Preventive Medicine, Monash University, Melbourne, Victoria, Australiaen
dc.identifier.affiliationSchool of Nursing and Midwifery, Deakin University, Melbourne, Australiaen
dc.identifier.affiliationDepartment of Anesthesiology and Resuscitology, Okayama University Hospital, Okayama, Japanen
dc.identifier.affiliationDepartment of Intensive Care, Hospital Universitari Mutua Terrassa, Barcelona, Spainen
dc.identifier.affiliationDepartment of Intensive Care Medicine and Burn Center, Centre Hospitalier Universitaire Vaudois, LaUSAnne, Switzerlanden
dc.identifier.doi10.1016/j.jcrc.2014.09.022en
dc.description.pages138-44en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/25449882en
dc.type.austinJournal Articleen
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptIntensive Care-
crisitem.author.deptIntensive Care-
crisitem.author.deptData Analytics Research and Evaluation (DARE) Centre-
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