Please use this identifier to cite or link to this item:
Title: Preoperative atrial fibrillation is an independent predictor of worse early and late outcomes after isolated coronary artery bypass graft surgery.
Austin Authors: Saxena, Akshat;Kapoor, Jada;Dinh, Diem T;Smith, Julian A;Shardey, Gilbert C;Newcomb, Andrew E
Affiliation: Department of Surgery (MMC), Monash University, Clayton, Victoria, Australia
Department of Cardiothoracic Surgery, St Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia
Department of Cardiothoracic Surgery, Monash Medical Centre, Clayton, Victoria, Australia
University of Melbourne, Department of Surgery, St Vincent's Hospital Melbourne, Fitzroy, Victoria, Australia
Department of Surgery, Austin Hospital, Heidelberg, Victoria, Australia
Department of Epidemiology and Preventative Medicine, Monash University, Prahran, Victoria, Australia
Cabrini Medical Centre, Malvern, Victoria, Australia
Issue Date: 3-Jul-2014
Publication information: Journal of Cardiology 2014; 65(3): 224-9
Abstract: To evaluate the impact of preoperative atrial fibrillation (pre-op AF) on early and late mortality after isolated coronary artery bypass graft (CABG) surgery.Data obtained prospectively between June 2001 and December 2009 by the Australasian Society of Cardiac and Thoracic Surgeons National Cardiac Surgery Database Program were retrospectively analyzed. Patients who underwent concomitant atrial arrhythmia surgery/ablation were excluded. Demographic and operative data were compared between patients with and without pre-op AF. The independent association of pre-op AF on early mortality, perioperative complications, and late mortality was determined.Isolated CABG surgery was performed in 21,534 patients; 1312 (6.1%) presented with pre-op AF. Pre-op AF patients were older (mean age, 71 years vs. 65 years, p<0.001) and had more comorbidities reflected in a higher additive EuroSCORE (8.4±3.5 vs. 6.5±3.2, p=0.001). Even after accounting for confounding factors, however, pre-op AF was associated with a 63% increase in 30-day mortality [4.2% vs. 1.4%; hazard ratio (HR), 1.63; 95% confidence interval (CI), 1.17-2.29; p=0.004] and 39% increase in late mortality (5-year survival, 78% vs. 90%; HR, 1.39; 95% CI, 1.20-1.61; p<0.001).Pre-op AF is an independent predictor of poor early and late outcomes. Pre-op AF should be considered, therefore, in the development or update of risk stratification models for CABG surgery.
Gov't Doc #: 24998984
DOI: 10.1016/j.jjcc.2014.06.003
Type: Journal Article
Subjects: Atrial fibrillation
Cardiac surgery
Coronary artery bypass graft
Appears in Collections:Journal articles

Show full item record

Google ScholarTM


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.