Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12185
Full metadata record
DC FieldValueLanguage
dc.contributor.authorGreen, Jessica Emilyen
dc.contributor.authorAriathianto, Yohanesen
dc.contributor.authorWong, Si Munen
dc.contributor.authorAboltins, Craig Aen
dc.contributor.authorLim, Kwangen
dc.date.accessioned2015-05-16T01:50:21Z
dc.date.available2015-05-16T01:50:21Z
dc.date.issued2014-04-23en
dc.identifier.citationBmc Geriatrics 2014; 14(): 55en
dc.identifier.govdoc24754903en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/12185en
dc.description.abstractGiven the increasing incidence of bacteraemia causing significant morbidity and mortality in older patients, this study aimed to compare the clinical features, laboratory findings and mortality of patients over the age of 80 to younger adults.This study was a retrospective, observational study. Participants were taken to be all patients aged 18 and above with confirmed culture positive sepsis, admitted to a large metropolitan hospital in the year 2010. Measurements taken included patient demographics (accommodation, age, sex, comorbidities), laboratory investigations (white cell count, neutrophil count, C-reactive protein, microbiology results), clinical features (vital signs, presence of localising symptoms, complications, place of acquisition).A total of 1367 patient episodes were screened and 155 met study inclusion criteria. There was no statistically significant difference between likelihood of fever or systolic blood pressure between younger and older populations (p-values of 0.81 and 0.64 respectively). Neutrophil count was higher in the older cohort (p = 0.05). Higher Charlson (J Chronic Dis 40(5):373-383, 1987) comorbidity index, greater age and lower systolic blood pressure were found to be statistically significant predictors of mortality (p-values of 0.01, 0.02 and 0.03 respectively).The findings of this study indicate older patients are more likely to present without localising features. However, importantly, there is no significant difference in the likelihood of fever or inflammatory markers. This study also demonstrates the importance of the Charlson Index of Comorbidities (J Chronic Dis 40(5):373-383, 1987) as a predictive factor for mortality, with age and hypotension being less important but statistically significant predictive factors of mortality.en
dc.language.isoenen
dc.subject.otherAdolescenten
dc.subject.otherAdulten
dc.subject.otherAgeden
dc.subject.otherAged, 80 and overen
dc.subject.otherBacteremia.blood.diagnosis.epidemiologyen
dc.subject.otherCohort Studiesen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherInflammation Mediators.blooden
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherRetrospective Studiesen
dc.subject.otherYoung Adulten
dc.titleClinical and inflammatory response to bloodstream infections in octogenarians.en
dc.typeJournal Articleen
dc.identifier.journaltitleBMC geriatricsen
dc.identifier.affiliationAustin Health, 145 Studley Rd, Heidelberg 3084, Australiaen
dc.identifier.doi10.1186/1471-2318-14-55en
dc.description.pages55en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/24754903en
dc.type.austinJournal Articleen
item.grantfulltextopen-
item.languageiso639-1en-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.openairetypeJournal Article-
item.fulltextWith Fulltext-
item.cerifentitytypePublications-
Appears in Collections:Journal articles
Files in This Item:
File Description SizeFormat 
24754903.pdf234.22 kBAdobe PDFThumbnail
View/Open
Show simple item record

Download(s)

38
checked on Feb 6, 2023

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.