Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/12112
Full metadata record
DC FieldValueLanguage
dc.contributor.authorKanaan, Richard A Aen
dc.contributor.authorChaddock, Christopheren
dc.contributor.authorAllin, Matthewen
dc.contributor.authorPicchioni, Marco Men
dc.contributor.authorDaly, Eileenen
dc.contributor.authorShergill, Sukhi Sen
dc.contributor.authorMcGuire, Philip Ken
dc.date.accessioned2015-05-16T01:45:38Z
dc.date.available2015-05-16T01:45:38Z
dc.date.issued2014-03-06en
dc.identifier.citationPLoS One 2014; 9(3): e91109en
dc.identifier.govdoc24603769en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/12112en
dc.description.abstractSexual dimorphism in human brain structure is well recognised, but less is known about gender differences in white matter microstructure. We used diffusion tensor imaging to explore gender differences in fractional anisotropy (FA), an index of microstructural integrity. We previously found increased FA in the corpus callosum in women, and increased FA in the cerebellum and left superior longitudinal fasciculus (SLF) in men, using a whole-brain voxel-based analysis.A whole-brain tract-based spatial statistics analysis of 120 matched subjects from the previous analysis, and 134 new subjects (147 men and 107 women in total) using a 1.5T scanner, with division into tract-based regions of interest.Men had higher FA in the superior cerebellar peduncles and women had higher FA in corpus callosum in both the first and second samples. The higher SLF FA in men was not found in either sample.We confirmed our previous, controversial finding of increased FA in the corpus callosum in women, and increased cerebellar FA in men. The corpus callosum FA difference offers some explanation for the otherwise puzzling advantage in inter-callosal transfer time shown in women; the cerebellar FA difference may be associated with the developmental motor advantage shown in men.en
dc.language.isoenen
dc.subject.otherAdolescenten
dc.subject.otherAdulten
dc.subject.otherAnisotropyen
dc.subject.otherDemographyen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherMaleen
dc.subject.otherMiddle Ageden
dc.subject.otherPyramidal Tracts.pathologyen
dc.subject.otherSex Characteristicsen
dc.subject.otherStatistics as Topicen
dc.subject.otherWhite Matter.pathologyen
dc.subject.otherYoung Adulten
dc.titleGender influence on white matter microstructure: a tract-based spatial statistics analysis.en
dc.typeJournal Articleen
dc.identifier.journaltitlePLoS Oneen
dc.identifier.affiliationDepartment of Psychiatry, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australiaen
dc.identifier.affiliationKing's College London, Institute of Psychiatry, Department of Psychosis Studies, London, United Kingdom.en
dc.identifier.affiliationKing's College London, Institute of Psychiatry, Department of Psychosis Studies, London, United Kingdom; St Andrew's Academic Centre, King's College London, Northampton, United Kingdom.en
dc.identifier.affiliationKing's College London, Institute of Psychiatry, Department of Developmental Psychiatry, London, United Kingdom.en
dc.identifier.doi10.1371/journal.pone.0091109en
dc.description.pagese91109en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/24603769en
dc.identifier.orcid0000-0003-0992-1917-
dc.type.austinJournal Articleen
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptPsychiatry (University of Melbourne)-
Appears in Collections:Journal articles
Show simple item record

Page view(s)

6
checked on Feb 3, 2023

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.