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dc.contributor.authorKao, Yung Hsiangen
dc.contributor.authorLo, Richard H Gen
dc.contributor.authorTay, Kiang Hiongen
dc.contributor.authorTan, Bien Sooen
dc.contributor.authorChow, Pierce K Hen
dc.contributor.authorNg, David C Een
dc.contributor.authorGoh, Anthony S Wen
dc.identifier.citationFrontiers in Oncology 2014; 4(): 11en
dc.description.abstractHigh resolution yttrium-90 ((90)Y) imaging of post-radioembolization microsphere biodistribution may be achieved by conventional positron emission tomography with integrated computed tomography (PET/CT) scanners that have time-of-flight capability. However, reconstructed (90)Y PET/CT images have high background noise, making non-target activity detection technically challenging. This educational article describes our image assessment technique for non-target activity detection by (90)Y PET/CT, which qualitatively overcomes the problem of background noise. We present selected case examples of non-target activity in untargeted liver, stomach, gallbladder, chest wall, and kidney, supported by angiography and (90)Y bremsstrahlung single-photon emission computed tomography with integrated computed tomography (SPECT/CT) or technetium-99m macroaggregated albumin SPECT/CT.en
dc.subject.otherbremsstrahlung SPECT/CTen
dc.subject.otherdiagnostic reporting techniqueen
dc.subject.othernon-target activityen
dc.subject.otherselective internal radiation therapyen
dc.subject.otheryttrium-90 PET/CTen
dc.subject.otheryttrium-90 radioembolizationen
dc.subject.otheryttrium-90 resin microspheresen
dc.titleNon-Target Activity Detection by Post-Radioembolization Yttrium-90 PET/CT: Image Assessment Technique and Case Examples.en
dc.typeJournal Articleen
dc.identifier.journaltitleFrontiers in oncologyen
dc.identifier.affiliationDepartment of Nuclear Medicine and PET , Singapore General Hospital , Singapore ; Department of Nuclear Medicine, Austin Hospital , Melbourne, VIC , Australiaen
dc.identifier.affiliationDepartment of Diagnostic Radiology , Singapore General Hospital , Singapore.en
dc.identifier.affiliationDepartment of General Surgery , Singapore General Hospital , Singapore ; Department of Surgical Oncology , National Cancer Centre Singapore , Singapore ; Office of Clinical Sciences , Duke-NUS Graduate Medical School , Singapore.en
dc.identifier.affiliationDepartment of Nuclear Medicine and PET , Singapore General Hospital , Singapore.en
dc.type.austinJournal Articleen
item.openairetypeJournal Article-
item.fulltextNo Fulltext-
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