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|Title:||Non-Target Activity Detection by Post-Radioembolization Yttrium-90 PET/CT: Image Assessment Technique and Case Examples.||Austin Authors:||Kao, Yung Hsiang;Lo, Richard H G;Tay, Kiang Hiong;Tan, Bien Soo;Chow, Pierce K H;Ng, David C E;Goh, Anthony S W||Affiliation:||Department of Nuclear Medicine and PET , Singapore General Hospital , Singapore ; Department of Nuclear Medicine, Austin Hospital , Melbourne, VIC , Australia
Department of Diagnostic Radiology , Singapore General Hospital , Singapore.
Department of General Surgery , Singapore General Hospital , Singapore ; Department of Surgical Oncology , National Cancer Centre Singapore , Singapore ; Office of Clinical Sciences , Duke-NUS Graduate Medical School , Singapore.
Department of Nuclear Medicine and PET , Singapore General Hospital , Singapore.
|Issue Date:||3-Feb-2014||Publication information:||Frontiers in Oncology 2014; 4(): 11||Abstract:||High resolution yttrium-90 ((90)Y) imaging of post-radioembolization microsphere biodistribution may be achieved by conventional positron emission tomography with integrated computed tomography (PET/CT) scanners that have time-of-flight capability. However, reconstructed (90)Y PET/CT images have high background noise, making non-target activity detection technically challenging. This educational article describes our image assessment technique for non-target activity detection by (90)Y PET/CT, which qualitatively overcomes the problem of background noise. We present selected case examples of non-target activity in untargeted liver, stomach, gallbladder, chest wall, and kidney, supported by angiography and (90)Y bremsstrahlung single-photon emission computed tomography with integrated computed tomography (SPECT/CT) or technetium-99m macroaggregated albumin SPECT/CT.||Gov't Doc #:||24551594||URI:||http://ahro.austin.org.au/austinjspui/handle/1/12086||DOI:||10.3389/fonc.2014.00011||URL:||https://pubmed.ncbi.nlm.nih.gov/24551594||Type:||Journal Article||Subjects:||SIR-spheres
diagnostic reporting technique
selective internal radiation therapy
yttrium-90 resin microspheres
|Appears in Collections:||Journal articles|
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