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Title: | Clinical factors are significant predictors of outcome post intra-arterial therapy for acute ischaemic stroke: a review. | Austin Authors: | Lee, Wei-I;Mitchell, Peter;Dowling, Richard;Yan, Bernard | Affiliation: | Austin Hospital, 145 Studley Road, Heidelberg, Victoria 3084, Australia | Issue Date: | 14-Nov-2013 | Publication information: | Journal of Neuroradiology. Journal De Neuroradiologie 2013; 40(5): 315-25 | Abstract: | Intra-arterial therapy (IAT) provides superior recanalisation rates, approaching 80% for the current generation of endovascular devices. Furthermore, IAT may allow for an extended therapeutic window beyond that which is permissible for intravenous thrombolysis. However, the improved recanalisation rates are not matched by concordant clinical outcomes, leading to an invigorated search for predictors of clinical outcome. There is emerging evidence that younger age, mild-moderate stroke, and shorter vessel occlusion time are associated with better clinical outcome after IAT. This review aims to critically appraise current evidence that may inform changes in the selective inclusion of clinical factors in the future design and trial of IAT. | Gov't Doc #: | 24239412 | URI: | https://ahro.austin.org.au/austinjspui/handle/1/11943 | DOI: | 10.1016/j.neurad.2013.09.002 | Journal: | Journal of neuroradiology. Journal de neuroradiologie | URL: | https://pubmed.ncbi.nlm.nih.gov/24239412 | Type: | Journal Article | Subjects: | Acute ischaemic stroke Intra-arterial therapy Recanalisation Age Distribution Brain Ischemia.mortality.therapy Cerebral Revascularization.mortality Fibrinolytic Agents.administration & dosage Humans Injections, Intra-Arterial Outcome Assessment (Health Care).methods.statistics & numerical data Prevalence Prognosis Proportional Hazards Models Randomized Controlled Trials as Topic Reproducibility of Results Risk Factors Sensitivity and Specificity Sex Distribution Stroke.mortality.therapy Survival Rate Treatment Outcome |
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