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Title: Clinical factors are significant predictors of outcome post intra-arterial therapy for acute ischaemic stroke: a review.
Austin Authors: Lee, Wei-I;Mitchell, Peter;Dowling, Richard;Yan, Bernard
Affiliation: Austin Hospital, 145 Studley Road, Heidelberg, Victoria 3084, Australia
Issue Date: 14-Nov-2013
Publication information: Journal of Neuroradiology. Journal De Neuroradiologie 2013; 40(5): 315-25
Abstract: Intra-arterial therapy (IAT) provides superior recanalisation rates, approaching 80% for the current generation of endovascular devices. Furthermore, IAT may allow for an extended therapeutic window beyond that which is permissible for intravenous thrombolysis. However, the improved recanalisation rates are not matched by concordant clinical outcomes, leading to an invigorated search for predictors of clinical outcome. There is emerging evidence that younger age, mild-moderate stroke, and shorter vessel occlusion time are associated with better clinical outcome after IAT. This review aims to critically appraise current evidence that may inform changes in the selective inclusion of clinical factors in the future design and trial of IAT.
Gov't Doc #: 24239412
DOI: 10.1016/j.neurad.2013.09.002
Journal: Journal of neuroradiology. Journal de neuroradiologie
Type: Journal Article
Subjects: Acute ischaemic stroke
Intra-arterial therapy
Age Distribution
Brain Ischemia.mortality.therapy
Cerebral Revascularization.mortality
Fibrinolytic Agents.administration & dosage
Injections, Intra-Arterial
Outcome Assessment (Health Care).methods.statistics & numerical data
Proportional Hazards Models
Randomized Controlled Trials as Topic
Reproducibility of Results
Risk Factors
Sensitivity and Specificity
Sex Distribution
Survival Rate
Treatment Outcome
Appears in Collections:Journal articles

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