Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/11492
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dc.contributor.authorHolmes, Natasha E-
dc.contributor.authorJohnson, Paul D R-
dc.contributor.authorHowden, Benjamin P-
dc.date.accessioned2015-05-16T01:06:18Z
dc.date.available2015-05-16T01:06:18Z
dc.date.issued2012-05-16-
dc.identifier.citationJournal of Clinical Microbiology 2012; 50(8): 2548-52en_US
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/11492en
dc.description.abstractVancomycin has been used successfully for over 50 years for the treatment of Staphylococcus aureus infections, particularly those involving methicillin-resistant S. aureus. It has proven remarkably reliable, but its efficacy is now being questioned with the emergence of strains of S. aureus that display heteroresistance, intermediate resistance, and, occasionally, complete vancomycin resistance. More recently, an association has been established between poor outcome and infections with strains of S. aureus with an elevated vancomycin MIC within the susceptible range. This minireview summarizes the definitions, mechanisms, clinical impact, and laboratory identification of reduced vancomycin susceptibility in S. aureus and discusses practical issues for the diagnostic laboratory in testing and interpreting vancomycin susceptibility for S. aureus infections.en_US
dc.language.isoenen
dc.subject.otherAnti-Bacterial Agents.therapeutic useen
dc.subject.otherHumansen
dc.subject.otherMicrobial Sensitivity Testsen
dc.subject.otherStaphylococcal Infections.diagnosis.drug therapy.microbiologyen
dc.subject.otherStaphylococcus aureus.drug effectsen
dc.subject.otherTreatment Outcomeen
dc.subject.otherVancomycin Resistanceen
dc.titleRelationship between vancomycin-resistant Staphylococcus aureus, vancomycin-intermediate S. aureus, high vancomycin MIC, and outcome in serious S. aureus infections.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleJournal of Clinical Microbiologyen_US
dc.identifier.affiliationInfectious Diseasesen_US
dc.identifier.doi10.1128/JCM.00775-12en_US
dc.description.pages2548-52en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/22593595en
dc.type.contentTexten_US
dc.type.austinJournal Articleen
local.name.researcherHolmes, Natasha E
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptInfectious Diseases-
crisitem.author.deptData Analytics Research and Evaluation (DARE) Centre-
crisitem.author.deptInfectious Diseases-
crisitem.author.deptInfectious Diseases-
crisitem.author.deptMicrobiology-
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