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Title: Prospective audit of patients with haemophilia: bleeding episodes and management.
Austin Authors: Alexander, Matthew;Barnes, Chris;Barnett, Peter
Affiliation: Department of Orthopaedics, Austin Hospital, Melbourne, Victoria, Australia
Issue Date: 12-May-2011
Publication information: Journal of Paediatrics and Child Health 2011; 48(2): 177-9
Abstract: Haemophilia is a congenital bleeding disorder that requires replacement of factor VIII (haemophilia A) or factor IX (haemophilia B) via intravenous infusions. Children can either be treated with prophylactic treatment to prevent bleeding or be managed with on-demand therapy and treat specific bleeding episodes.The aim of this paper was to prospectively follow a cohort of haemophilia patients to determine the incidence of bleeding, re-bleeding, re-treatment and adjunct management over a period of 5 months.Sixty-six boys with haemophilia were followed. Age range was 10 months to 19 years; 70% of patients had severe haemophilia and 38 (58%) of all patients were on prophylaxis.Twenty-nine patients experienced at least one episode of bleeding during study period which included 70 home bleeding episodes and 20 emergency department (ED) presentations. Secondary treatments occurred in 38% of all bleeding episodes. The incidence of re-bleeds occurring within 3 weeks of the initial bleeding episode was 11%.Further study focusing on optimising treatment regimes for patients with haemophilia presenting with bleeding episodes is necessary.
Gov't Doc #: 21564382
DOI: 10.1111/j.1440-1754.2011.02064.x
Type: Journal Article
Subjects: Adolescent
Child, Preschool
Disease Management
Hemophilia A.complications.therapy
Hemophilia B.complications.therapy
Medical Audit
Prospective Studies
Treatment Outcome
Young Adult
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