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Title: Evaluation of the Xpert™ MRSA/SA Blood Culture assay for the detection of Staphylococcus aureus including strains with reduced vancomycin susceptibility from blood culture specimens.
Austin Authors: Kelley, Peter G;Grabsch, Elizabeth A ;Farrell, Jenny;Xie, Shirley;Montgomery, Janet;Mayall, Barrie C;Howden, Benjamin P 
Affiliation: Microbiology, Austin Health, Victoria, Australia
Issue Date: 15-Apr-2011
Publication information: Diagnostic Microbiology and Infectious Disease 2011; 70(3): 404-7
Abstract: The Xpert MRSA/SA Blood Culture (BC) assay (Cepheid, Sunnyvale, CA) was prospectively compared to culture and found to have excellent specificity for both Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) in BC specimens with a sensitivity of 75% (3/4) and 100% (17/17), respectively. Among 28 heterogeneous vancomycin-intermediate S. aureus (hVISA)/VISA spiked BCs, the assay correctly identified 84.6% VISA and 80% hVISA isolates as MRSA.
Gov't Doc #: 21497042
DOI: 10.1016/j.diagmicrobio.2011.02.006
Type: Journal Article
Subjects: Adolescent
Aged, 80 and over
Bacteriological Techniques.methods
Drug Resistance, Bacterial
Middle Aged
Sensitivity and Specificity
Staphylococcal Infections.microbiology
Staphylococcus aureus.drug effects.isolation & purification
Young Adult
Appears in Collections:Journal articles

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