Austin Health

Title
Evaluation of the Xpert™ MRSA/SA Blood Culture assay for the detection of Staphylococcus aureus including strains with reduced vancomycin susceptibility from blood culture specimens.
Publication Date
2011-04-15
Author(s)
Kelley, Peter G
Grabsch, Elizabeth A
Farrell, Jenny
Xie, Shirley
Montgomery, Janet
Mayall, Barrie C
Howden, Benjamin P
Type of document
Journal Article
OrcId
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DOI
10.1016/j.diagmicrobio.2011.02.006
Abstract
The Xpert MRSA/SA Blood Culture (BC) assay (Cepheid, Sunnyvale, CA) was prospectively compared to culture and found to have excellent specificity for both Staphylococcus aureus and methicillin-resistant S. aureus (MRSA) in BC specimens with a sensitivity of 75% (3/4) and 100% (17/17), respectively. Among 28 heterogeneous vancomycin-intermediate S. aureus (hVISA)/VISA spiked BCs, the assay correctly identified 84.6% VISA and 80% hVISA isolates as MRSA.
Link
Citation
Diagnostic Microbiology and Infectious Disease 2011; 70(3): 404-7
Jornal Title
Diagnostic Microbiology and Infectious Disease

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