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Title: Gene sequencing and tissue expression of unknown isoforms of an angiotensin II type 2 receptor interacting protein, ATIP, in the rat.
Austin Authors: Krezel, Michael Angus;Rezmann, Linda Adriana;Varghayee, Naghmeh;Pete, Josefa;Frauman, Albert G ;Louis, Simon Nicholas Stewart
Affiliation: Clinical Pharmacology and Therapeutics Unit, University of Melbourne, Department of Medicine, Austin Health, Heidelberg, Victoria, Australia
Issue Date: 7-Mar-2011
Publication information: Bioscience, Biotechnology, and Biochemistry 2011; 75(3): 414-8
Abstract: To investigate the expression of the unknown angiotensin II type 2 receptor interacting protein (ATIP) isoforms in the rat we used the known sequences of human and mouse ATIP to design sequencing primers to enable us to sequence rat ATIP3 and ATIP4. Exon 4, which is present in human but not mouse ATIP, was not identified in the coding region of rat ATIP. The expression levels of these genes in a range of rat tissues were examined, and we concluded that there is little similarity in the relative tissue distribution of the various ATIP isoforms in rat and human.
Gov't Doc #: 21389599
DOI: 10.1271/bbb.100176
Type: Journal Article
Subjects: Amino Acid Sequence
Base Sequence
Blotting, Western
Cell Line
Cloning, Molecular
DNA Primers.genetics.metabolism
Escherichia coli
Intracellular Signaling Peptides and Proteins.genetics.metabolism
Molecular Sequence Data
Organ Specificity
Polymerase Chain Reaction
Protein Isoforms.genetics.metabolism
RNA, Messenger.analysis.biosynthesis
Receptor, Angiotensin, Type 2.genetics.metabolism
Recombinant Proteins.genetics.metabolism
Sequence Homology, Amino Acid
Tumor Suppressor Proteins.genetics.metabolism
Appears in Collections:Journal articles

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