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Title: Culture of human endothelial cells.
Austin Authors: Gallicchio, M A
Affiliation: Department of Medicine, Austin and Repatriation Medical Centre, University of Melbourne, Heidelberg, Victoria, Australia
Issue Date: 2001
Publication information: Methods in Molecular Medicine; 52(): 147-61
Abstract: Endothelial cells line the luminal surface of all blood vessels in the body. The endothelial surface in adult humans is composed of approximately l-6×l0(13) cells and covers an area of 1-7 m(2). Endothelium serves many functions, including fluid and solute exchange through cell contraction, provision of an antithrombogenic surface through tissue plasminogen activator (tPA) and prostacyclin release, synthesis of angiogenic factors such as adenosine, allowance of leukocyte trafficking through adhesion molecule synthesis, presentation of antigens to the immune system, maintenance of vascular tone through nitric oxide and endothelin synthesis, and metabolism of circulating molecules through the release of enzymes such as lipoprotein lipase.
Gov't Doc #: 21340938
DOI: 10.1385/1-59259-073-X:147
Type: Journal Article
Appears in Collections:Journal articles

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