Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/10911
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dc.contributor.authorLim, Eu Jin-
dc.contributor.authorGow, Paul J-
dc.contributor.authorAngus, Peter W-
dc.date.accessioned2015-05-16T00:29:18Z
dc.date.available2015-05-16T00:29:18Z
dc.date.issued2009-11-01-
dc.identifier.citationLiver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society; 15(11): 1508-13en_US
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/10911en
dc.description.abstractEndoscopic variceal ligation (EVL) is widely used to prevent esophageal variceal bleeding in patients with advanced cirrhosis. However, the safety and efficacy of EVL in this setting have not been clearly established. This study included 300 adult patients with cirrhosis on our liver transplant waitlist who underwent upper gastrointestinal endoscopy. Esophageal varices deemed to be at high risk of bleeding were banded until eradication or transplantation. A retrospective review of patient notes and endoscopy databases was undertaken, and the number of banding episodes, complications, and patient outcomes were recorded. Forty-two of 300 patients presented with or had previous variceal bleeding prior to referral and were excluded from the analysis. Of the remaining 258 patients, 101 underwent a total of 259 banding episodes (2.6 per patient) with a median follow-up post-banding of 18.4 months per patient (a total of 150 patient years). Failed prophylaxis occurred in 2 patients (2%), and there were 3 episodes (1.2%) of acute hematemesis from band-induced ulceration. One patient (1%) had mild esophageal stricturing post-banding without dysphagia. Four of 36 patients (11%) previously found to have moderately sized or larger varices that were not banded presented with hematemesis due to variceal bleeding and were subsequently banded. None of the patients that received banding died because of bleeding or failed to receive a transplant as a result of banding complications. This study shows that in liver transplant candidates, EVL is highly effective in preventing first variceal bleed. Although banding carries a small risk of band-induced bleeding, this rate is low in comparison with the predicted rate of variceal bleeding in this population.en_US
dc.language.isoenen
dc.subject.otherAdolescenten
dc.subject.otherAdulten
dc.subject.otherAgeden
dc.subject.otherCarcinoma, Hepatocellular.surgeryen
dc.subject.otherEndoscopy.methodsen
dc.subject.otherEsophageal and Gastric Varices.complications.surgeryen
dc.subject.otherFemaleen
dc.subject.otherGastrointestinal Hemorrhage.etiology.prevention & controlen
dc.subject.otherHumansen
dc.subject.otherLigationen
dc.subject.otherLiver Neoplasms.surgeryen
dc.subject.otherLiver Transplantationen
dc.subject.otherMaleen
dc.subject.otherMedical Auditen
dc.subject.otherMiddle Ageden
dc.subject.otherPostoperative Complications.etiology.prevention & controlen
dc.subject.otherPreoperative Careen
dc.subject.otherRetrospective Studiesen
dc.subject.otherTreatment Outcomeen
dc.subject.otherWaiting Listsen
dc.subject.otherYoung Adulten
dc.titleEndoscopic variceal ligation for primary prophylaxis of esophageal variceal hemorrhage in pre-liver transplant patients.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleLiver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Societyen_US
dc.identifier.affiliationGastroenterology and Hepatologyen_US
dc.identifier.doi10.1002/lt.21857en_US
dc.description.pages1508-13en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/19877221en
dc.type.contentTexten_US
dc.type.austinJournal Articleen
local.name.researcherAngus, Peter W
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptVictorian Liver Transplant Unit-
crisitem.author.deptVictorian Liver Transplant Unit-
crisitem.author.deptGastroenterology and Hepatology-
crisitem.author.deptVictorian Liver Transplant Unit-
crisitem.author.deptGastroenterology and Hepatology-
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