Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/10842
Title: Identification of four different CD46 (MCP) molecules with anti-peptide antibodies.
Austin Authors: Purcell, D F;Jonstone, R W;McKenzie, Ian F C
Affiliation: Austin Research Institute, Austin Hospital, Heidelberg, Victoria, Australia
Issue Date: 31-Oct-1991
Publication information: Biochemical and Biophysical Research Communications; 180(2): 1091-7
Abstract: Four protein isoforms of the human CD46 molecule (MCP) have been identified using rabbit antisera against synthetic peptides corresponding to predicted cytoplasmic carboxyl-terminal sequences. Two different cytoplasmic tails, CD46 CYT 1 and CD46 CYT 2, were detected in CD46 molecules isolated from almost every cell type examined. Bands of 56 and 66 kDa were obtained from SDS-PAGE analyses of various cell types with both CYT 1 and CYT 2 antisera, which indicated that the size polymorphism of the CD46 molecule is not due to variations in the cytoplasmic tail and that each species contained two different sized molecules.
Gov't Doc #: 1953714
URI: http://ahro.austin.org.au/austinjspui/handle/1/10842
URL: https://pubmed.ncbi.nlm.nih.gov/1953714
Type: Journal Article
Subjects: Amino Acid Sequence
Animals
Antibodies
Antigen-Antibody Complex
Antigens, CD.analysis.genetics.immunology
Antigens, CD46
Electrophoresis, Gel, Two-Dimensional
Electrophoresis, Polyacrylamide Gel
Enzyme-Linked Immunosorbent Assay
Humans
Membrane Glycoproteins.analysis.genetics.immunology
Molecular Sequence Data
Peptides.chemical synthesis.immunology
Rabbits.immunology
Appears in Collections:Journal articles

Show full item record

Google ScholarTM

Check


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.