Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/10254
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dc.contributor.authorBagshaw, Sean Men
dc.contributor.authorGalbraith, P Dianeen
dc.contributor.authorMitchell, L Brenten
dc.contributor.authorSauve, Regen
dc.contributor.authorExner, Derek Ven
dc.contributor.authorGhali, William Aen
dc.date.accessioned2015-05-15T23:38:43Z
dc.date.available2015-05-15T23:38:43Z
dc.date.issued2006-11-01en
dc.identifier.citationThe Annals of Thoracic Surgery; 82(5): 1927-37en
dc.identifier.govdoc17062287en
dc.identifier.otherPUBMEDen
dc.identifier.urihttp://ahro.austin.org.au/austinjspui/handle/1/10254en
dc.description.abstractAmiodarone has been proposed to decrease atrial fibrillation after cardiac surgery. The literature was systematically reviewed for randomized trials comparing amiodarone with control for prevention of atrial fibrillation. Data were extracted on study characteristics, quality, and incidence of atrial fibrillation, cardiovascular outcomes, and length of hospitalization. Nineteen trials were included. Amiodarone reduced the odds ratio of atrial fibrillation (0.50; 95% confidence interval [CI]: 0.43 to 0.59, p < 0.0001), ventricular tachyarrhythmias (0.39; 95% CI: 0.26 to 0.58, p < 0.0001), and strokes (0.53; 95% CI: 0.30 to 0.92, p = 0.02). Amiodarone reduced hospital stay (0.6 days; 95% CI: 0.4 to 0.8, p < 0.0001). Amiodarone decreased atrial fibrillation, reduced perioperative ventricular tachyarrhythmias and strokes, and reduced duration of hospitalization. The current evidence supports recommending the routine use of perioperative amiodarone for cardiac surgery.en
dc.language.isoenen
dc.subject.otherAdrenergic beta-Antagonists.therapeutic useen
dc.subject.otherAmiodarone.therapeutic useen
dc.subject.otherAnti-Arrhythmia Agents.therapeutic useen
dc.subject.otherAtrial Fibrillation.epidemiology.etiology.prevention & controlen
dc.subject.otherCardiac Surgical Procedures.adverse effectsen
dc.subject.otherChemopreventionen
dc.subject.otherHumansen
dc.subject.otherIncidenceen
dc.subject.otherLength of Stayen
dc.subject.otherStroke.etiology.prevention & controlen
dc.titleProphylactic amiodarone for prevention of atrial fibrillation after cardiac surgery: a meta-analysis.en
dc.typeJournal Articleen
dc.identifier.journaltitleAnnals of Thoracic Surgeryen
dc.identifier.affiliationDepartment of Critical Care Medicine, University of Calgary, Calgary, Alberta, Canada; Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada; Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australiaen
dc.identifier.doi10.1016/j.athoracsur.2006.06.032en
dc.description.pages1927-37en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/17062287en
dc.type.austinJournal Articleen
item.grantfulltextnone-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.languageiso639-1en-
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