Please use this identifier to cite or link to this item:
https://ahro.austin.org.au/austinjspui/handle/1/10248
Full metadata record
DC Field | Value | Language |
---|---|---|
dc.contributor.author | Bellomo, Rinaldo | en |
dc.contributor.author | Bagshaw, Sean M | en |
dc.date.accessioned | 2015-05-15T23:38:15Z | - |
dc.date.available | 2015-05-15T23:38:15Z | - |
dc.date.issued | 2006 | en |
dc.identifier.citation | Critical Care; 10(5): 232 | en |
dc.identifier.govdoc | 17029653 | en |
dc.identifier.other | PUBMED | en |
dc.identifier.uri | https://ahro.austin.org.au/austinjspui/handle/1/10248 | en |
dc.description.abstract | The current approach to assessing the quality of evidence obtained from clinical trials focuses on three dimensions: the quality of the design (with double-blinded randomised controlled trials representing the highest level of such design); the statistical power (beta) and the level of significance (alpha). While these aspects are important, we argue that other significant aspects of trial quality impinge upon the truthfulness of the findings: biological plausibility, reproducibility and generalisability. We present several recent studies in critical care medicine where the design, beta and alpha components of the study are seemingly satisfactory but where the aspects of biological plausibility, reproducibility and generalisability show serious limitations. Accordingly, we argue for more reflection, definition and consensus on these aspects of the evaluation of evidence. | en |
dc.language.iso | en | en |
dc.subject.other | Evidence-Based Medicine.classification.methods | en |
dc.subject.other | Humans | en |
dc.subject.other | Randomized Controlled Trials as Topic.classification.methods | en |
dc.title | Evidence-based medicine: classifying the evidence from clinical trials--the need to consider other dimensions. | en |
dc.type | Journal Article | en |
dc.identifier.journaltitle | Critical Care | en |
dc.identifier.affiliation | Department of Intensive Care, Austin Hospital, Studley Rd, Heidelberg, Victoria 3084, Australia | en |
dc.identifier.doi | 10.1186/cc5045 | en |
dc.description.pages | 232 | en |
dc.relation.url | https://pubmed.ncbi.nlm.nih.gov/17029653 | en |
dc.type.austin | Journal Article | en |
local.name.researcher | Bellomo, Rinaldo | |
item.openairecristype | http://purl.org/coar/resource_type/c_18cf | - |
item.cerifentitytype | Publications | - |
item.fulltext | With Fulltext | - |
item.grantfulltext | open | - |
item.languageiso639-1 | en | - |
item.openairetype | Journal Article | - |
crisitem.author.dept | Intensive Care | - |
crisitem.author.dept | Data Analytics Research and Evaluation (DARE) Centre | - |
Appears in Collections: | Journal articles |
Files in This Item:
File | Description | Size | Format | |
---|---|---|---|---|
17029653.pdf | 68.96 kB | Adobe PDF | View/Open |
Page view(s)
14
checked on Mar 29, 2024
Download(s)
104
checked on Mar 29, 2024
Google ScholarTM
Check
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.