Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/9841
Title: Selective endoscopic cholangiography for the detection of common bile duct stones in patients with cholelithiasis.
Authors: Katz, D;Nikfarjam, Mehrdad;Sfakiotaki, A;Christophi, Christopher
Affiliation: Dept. of Surgery, University of Melbourne, Austin Hospital, Victoria, Australia.
Issue Date: 1-Dec-2004
Citation: Endoscopy; 36(12): 1045-9
Abstract: The detection and management of common bile duct (CBD) stones in patients undergoing laparoscopic cholecystectomy continues to be controversial. Several diagnostic and therapeutic strategies have been suggested. These include intraoperative cholangiography, selective endoscopic retrograde cholangiopancreatography (ERCP), magnetic resonance cholangiopancreatography, and endoscopic ultrasonography. The aim of this study was to evaluate the efficacy of selective ERCP in detecting CBD stones in patients with cholelithiasis before laparoscopic cholecystectomy.In a prospective study, patients with cholelithiasis who presented during a 6-year period were assessed on a selective basis with ERCP for suspected CBD stones before laparoscopic cholecystectomy. ERCP was carried out if the patient had any of the following criteria: a dilated CBD on ultrasound, gallstone pancreatitis, or abnormal liver function tests. Intraoperative cholangiography was not performed in any of the patients. Long-term follow-up was undertaken.The study included 427 patients. On the basis of selective criteria, ERCP was carried out in 41 patients (9.6 %), with confirmed CBD stones in 22 cases (53.7 %). The most useful predictor of CBD stones on ERCP was the presence of a dilated CBD in association with abnormal liver function tests. In this situation, CBD stones were identified in 14 of 17 cases (82 %). Abnormal liver function tests alone had a sensitivity of 50 % (four of eight). All other parameters used in isolation had a lower detection rate. During a median follow-up period of 6 years (range 1-10 years), six of 386 patients (1.6 %) with initially normal imaging and biochemical tests presented again with retained stones. All were successfully managed by ERCP and sphincterotomy. There were no major complications.Preoperative selective ERCP is effective in detecting clinically significant CBD stones. However, there is a high false-negative rate when a single criterion is used to guide therapy. Multivariate analysis of preoperative parameters for risk stratification, in conjunction with other imaging modalities, may make it possible to minimize unnecessary ERCPs.
Internal ID Number: 15578292
URI: http://ahro.austin.org.au/austinjspui/handle/1/9841
DOI: 10.1055/s-2004-825955
URL: http://www.ncbi.nlm.nih.gov/pubmed/15578292
Type: Journal Article
Subjects: Adult
Cholangiopancreatography, Endoscopic Retrograde
Cholecystectomy, Laparoscopic
Cholelithiasis.complications.radiography.surgery
Female
Follow-Up Studies
Gallstones.etiology.radiography.surgery
Humans
Male
Middle Aged
Predictive Value of Tests
Preoperative Care
Prospective Studies
Sphincterotomy, Endoscopic
Treatment Outcome
Appears in Collections:Journal articles

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