Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/9701
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dc.contributor.authorBradshaw, Jenniferen
dc.contributor.authorSaling, Michael Men
dc.contributor.authorHopwood, Men
dc.contributor.authorAnderson, Ven
dc.contributor.authorBrodtmann, Amyen
dc.date.accessioned2015-05-15T22:53:32Z
dc.date.available2015-05-15T22:53:32Z
dc.date.issued2004-03-01en
dc.identifier.citationJournal of Neurology, Neurosurgery, and Psychiatry; 75(3): 382-7en
dc.identifier.govdoc14966152en
dc.identifier.otherPUBMEDen
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/9701en
dc.description.abstractTo document and illustrate qualitative features of fluctuating cognition as described by care givers of patients with probable dementia with Lewy bodies (DLB) and Alzheimer's disease (AD). To determine whether the quality of the fluctuations differs between DLB and AD. To examine the clinical utility of two recently developed rating scales.Care givers of 13 patients with early probable DLB and 12 patients with early probable AD were interviewed using the Clinician Assessment of Fluctuation and the One Day Fluctuation Assessment Scale, both developed recently. Descriptions of fluctuating cognition were recorded verbatim, analysed, and rated.Descriptions of fluctuating cognition in DLB had a spontaneous, periodic, transient quality, which appeared to reflect an interruption in the ongoing flow of awareness or attention that impacted on functional abilities. Descriptions of fluctuations in AD frequently highlighted episodes of memory failure, or a more enduring state shift in the form of "good" and "bad" days, typically occurring in response to the cognitive demands of the immediate environment. These qualitative differences could be detected reliably by independent raters, but were not always captured in standard severity scores.Fluctuations occurring in DLB have particular characteristics that are distinguishable from fluctuations occurring in AD. Interpretation and application of the fluctuation criterion continues to limit the diagnostic sensitivity of the consensus criteria for DLB. Findings suggest that explicit documentation and a wider appreciation of these distinctions could improve the reliability with which less experienced clinicians identify this core diagnostic feature in the clinical setting.en
dc.language.isoenen
dc.subject.otherAgeden
dc.subject.otherAged, 80 and overen
dc.subject.otherAlzheimer Disease.complications.diagnosis.psychologyen
dc.subject.otherCaregiversen
dc.subject.otherCognition Disorders.etiology.psychologyen
dc.subject.otherDiagnosis, Differentialen
dc.subject.otherDisease Progressionen
dc.subject.otherFemaleen
dc.subject.otherHumansen
dc.subject.otherLewy Body Disease.complications.diagnosis.psychologyen
dc.subject.otherMaleen
dc.subject.otherPeriodicityen
dc.subject.otherSeverity of Illness Indexen
dc.titleFluctuating cognition in dementia with Lewy bodies and Alzheimer's disease is qualitatively distinct.en
dc.typeJournal Articleen
dc.identifier.journaltitleJournal of neurology, neurosurgery, and psychiatryen
dc.identifier.affiliationAustin Health, Heidelberg, Victoria, Australiaen
dc.description.pages382-7en
dc.relation.urlhttps://pubmed.ncbi.nlm.nih.gov/14966152en
dc.type.austinJournal Articleen
local.name.researcherBrodtmann, Amy
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptClinical Neuropsychology-
crisitem.author.deptThe Florey Institute of Neuroscience and Mental Health-
crisitem.author.deptThe Florey Institute of Neuroscience and Mental Health-
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