Please use this identifier to cite or link to this item:
|Title:||Capillary electrophoresis of hemoglobin.|
|Authors:||Jenkins, Margaret A;Ratnaike, Sujiva|
|Affiliation:||Division of Laboratory Medicine, Austin Health, Heidelberg, Australia. email@example.com|
|Citation:||Clinical Chemistry and Laboratory Medicine; 41(6): 747-54|
|Abstract:||Capillary electrophoresis (CE) has been used in a variety of in-house capillary isoelectric focusing (CIEF) and capillary zone electrophoresis (CZE) assays for the detection of hemoglobin (Hb) variants and the quantitation of HbA2 and HbF. A commercial kit has also been produced for the analysis of hemoglobin variants and thalassemia screening. Though CE methods have been shown to be able to detect many variants, final identification of the variant needs specialized testing such as DNA technology. Over the past 2 years, many instruments that had been used for these hemoglobin variant screening and thalassemia assays have been withdrawn from sale. Although CE HbA1c analysis is available, it cannot compete in turnaround time or cost with automated HPLC commercial instruments that give accurate HbA1c results in 3 or 4 minutes. Hence we do not anticipate a bright future for the analysis of hemoglobin by CE.|
|Internal ID Number:||12880137|
|Subjects:||Chromatography, High Pressure Liquid|
|Appears in Collections:||Journal articles|
Files in This Item:
There are no files associated with this item.
Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.