Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/9485
Title: Increased risk of cognitive impairment 3 months after mild to moderate first-ever stroke: a Community-Based Prospective Study of Nonaphasic English-Speaking Survivors.
Authors: Srikanth, Velandai K;Thrift, Amanda G;Saling, Michael M;Anderson, Jacqueline F I;Dewey, Helen M;Macdonell, Richard A L;Donnan, Geoffrey A
Institutional Author: Community-Based Prospective Study of Nonaphasic English-Speaking Survivors
Affiliation: Epidemiology Division, National Stroke Research Institute, Austin & Repatriation Medical Center, Melbourne, Australia. velandai.srikanth@utas.edu.au
Issue Date: 17-Apr-2003
Citation: Stroke; A Journal of Cerebral Circulation 2003; 34(5): 1136-43
Abstract: Results of hospital-based studies indicate a high risk of cognitive impairment 3 months after stroke. There are no comprehensive data on this issue from prospective community-based studies comparing first-ever stroke patients with stroke-free subjects.We administered a comprehensive neuropsychological battery to 99 community-based nonaphasic survivors of first-ever stroke at 3 months and 99 age- and sex-matched (1:1) stroke-free individuals. Domain-specific cognitive deficits were identified by blinded neuropsychological consensus.Stroke patients were more likely to suffer any cognitive impairment (relative risk [RR], 1.5; 95% CI, 1.1 to 2.1) attributable mainly to a greater risk of single-domain cognitive impairment (RR, 2.8; 95% CI, 1.5 to 5.3) but not multiple-domain cognitive impairment (RR, 1.2; 95% CI, 0.8 to 1.9).In this community-based study, a first-ever stroke of mild to moderate severity was associated with a significant risk of cognitive impairment at 3 months, even in the absence of clinical aphasia. This was due primarily to an increased risk of solitary deficits rather than generalized deficits.
Internal ID Number: 12702832
URI: http://ahro.austin.org.au/austinjspui/handle/1/9485
DOI: 10.1161/01.STR.0000069161.35736.39
URL: http://www.ncbi.nlm.nih.gov/pubmed/12702832
Type: Journal Article
Subjects: Adult
Aged
Aged, 80 and over
Cognition Disorders.epidemiology.etiology
Cohort Studies
Comorbidity
Cross-Sectional Studies
Diabetes Mellitus.epidemiology
Female
Follow-Up Studies
Hemiplegia.epidemiology.etiology
Humans
Hyperlipidemias.epidemiology
Hypertension.epidemiology
Male
Memory Disorders.epidemiology.etiology
Middle Aged
Neuropsychological Tests
Patient Selection
Prospective Studies
Risk
Selection Bias
Severity of Illness Index
Single-Blind Method
Stroke.complications.psychology
Survivors
Victoria.epidemiology
Appears in Collections:Journal articles

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