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|Title:||Increased risk of cognitive impairment 3 months after mild to moderate first-ever stroke: a Community-Based Prospective Study of Nonaphasic English-Speaking Survivors.|
|Authors:||Srikanth, Velandai K;Thrift, Amanda G;Saling, Michael M;Anderson, Jacqueline F I;Dewey, Helen M;Macdonell, Richard A L;Donnan, Geoffrey A|
|Institutional Author:||Community-Based Prospective Study of Nonaphasic English-Speaking Survivors|
|Affiliation:||Epidemiology Division, National Stroke Research Institute, Austin & Repatriation Medical Center, Melbourne, Australia. email@example.com|
|Citation:||Stroke; A Journal of Cerebral Circulation 2003; 34(5): 1136-43|
|Abstract:||Results of hospital-based studies indicate a high risk of cognitive impairment 3 months after stroke. There are no comprehensive data on this issue from prospective community-based studies comparing first-ever stroke patients with stroke-free subjects.We administered a comprehensive neuropsychological battery to 99 community-based nonaphasic survivors of first-ever stroke at 3 months and 99 age- and sex-matched (1:1) stroke-free individuals. Domain-specific cognitive deficits were identified by blinded neuropsychological consensus.Stroke patients were more likely to suffer any cognitive impairment (relative risk [RR], 1.5; 95% CI, 1.1 to 2.1) attributable mainly to a greater risk of single-domain cognitive impairment (RR, 2.8; 95% CI, 1.5 to 5.3) but not multiple-domain cognitive impairment (RR, 1.2; 95% CI, 0.8 to 1.9).In this community-based study, a first-ever stroke of mild to moderate severity was associated with a significant risk of cognitive impairment at 3 months, even in the absence of clinical aphasia. This was due primarily to an increased risk of solitary deficits rather than generalized deficits.|
|Internal ID Number:||12702832|
Aged, 80 and over
Severity of Illness Index
|Appears in Collections:||Journal articles|
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