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Title: Cade's observation of the antimanic effect of lithium and early Australian research.
Authors: Burrows, Graham D;Tiller, J W
Affiliation: University of Melbourne, Austin and Repatriation Medical Centre, Heidelberg, Victoria, Australia
Issue Date: 1-Dec-1999
Citation: The Australian and New Zealand Journal of Psychiatry; 33 Suppl(): S27-31
Abstract: John Cade had a major influence on the treatment of affective disorders following his report in 1949. His discovery of the efficacy of lithium as an antimanic agent was the result of an inevitable progression from the hypothesis of a metabolic basis for mania to clinical trials. Starting with animal studies, he progressed to patients. Further reports on lithium in the Medical Journal of Australia quickly followed in 1950 and 1951. The present paper reports on these and other Australian studies over the next few years. Lithium has moved in 50 years from a novel status to an internationally recognised major treatment of affective disorders.
Internal ID Number: 10622176
Type: Journal Article
Subjects: Antimanic Agents.history.pharmacology.therapeutic use
Bipolar Disorder.drug therapy.history.physiopathology
History, 20th Century
Lithium Carbonate.history.pharmacology.therapeutic use
Periodicals as Topic.history
Appears in Collections:Journal articles

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