Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/9175
Title: Secondary mania in patients with HIV infection.
Authors: Ellen, S R;Judd, F K;Mijch, A M;Cockram, A
Affiliation: Department of Psychiatry, University of Melbourne, Austin and Repatriation Medical Centre, Heidelberg, Victoria, Australia. sellen@austin.unimelb.edu.au
Issue Date: 1-Jun-1999
Citation: The Australian and New Zealand Journal of Psychiatry; 33(3): 353-60
Abstract: The aim of this study was to identify a cohort of patients with mania secondary to HIV infection, to describe the clinical and radiological features of HIV-related mania, and to describe the treatment outcome of the patients.All patients referred to the HIV consultation-liaison psychiatry service over the 29-month period from January 1993 to June 1995 were screened for the presence of manic symptoms. Diagnosis of mania was made according to DSM-III-R. Cases were defined as secondary mania if there was no clear history of mood disorder, and no family history of mood disorder. Cases were interviewed by the treating psychiatry registrar and psychiatrist to obtain information regarding present and past psychiatric history and family history of psychiatric disorder. The psychiatry registrar and consultant determined treatment.Twenty-three patients with mania were identified; 19 were considered to have secondary mania. The prevalence of secondary mania over the 29 months was 1.2% for HIV-positive patients, and 4.3% for those with AIDS. The clinical characteristics and response to treatment appeared to be similar to mania associated with bipolar affective disorder (primary mania). Neuroradiological abnormalities were common, occurring in 10 of the 19 patients, but did not appear to be clinically relevant. Cognitive impairment developed in five of the 15 patients where follow-up was possible.Mania occurring in advanced HIV disease appears to be more common than expected from epidemiological data regarding bipolar affective disorder. Differentiating secondary from primary mania has implications for the management and prognosis of mania.
Internal ID Number: 10442791
URI: http://ahro.austin.org.au/austinjspui/handle/1/9175
URL: http://www.ncbi.nlm.nih.gov/pubmed/10442791
Type: Journal Article
Subjects: Adult
Behavioral Symptoms
Bipolar Disorder.diagnosis.drug therapy.epidemiology.etiology
Brain.pathology
Cohort Studies
Diagnosis, Differential
Female
HIV Infections.complications.diagnosis.epidemiology
Humans
Irritable Mood
Male
Middle Aged
Pilot Projects
Prevalence
Psychotropic Drugs.therapeutic use
Risk Factors
Treatment Outcome
Victoria.epidemiology
Appears in Collections:Journal articles

Files in This Item:
There are no files associated with this item.


Items in AHRO are protected by copyright, with all rights reserved, unless otherwise indicated.