Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/22995
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dc.contributor.authorPefanis, Aspasia-
dc.contributor.authorWilliams, David S-
dc.contributor.authorSkrzypek, H-
dc.contributor.authorFung, A-
dc.contributor.authorPaizis, Kathy-
dc.date2018-07-26-
dc.date.accessioned2020-04-17T00:40:14Z-
dc.date.available2020-04-17T00:40:14Z-
dc.date.issued2020-03-
dc.identifier.citationObstetric Medicine 2020en_US
dc.identifier.issn1753-495X-
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/22995-
dc.description.abstractAntineutrophil cytoplasm antibody (ANCA)-associated vasculitides are rare small vessel vasculitides of unknown cause. The pathogenic role of MPO-ANCA in the vasculitides has been supported using various animal models, with B-cells playing a role in the disease pathogenesis. Pregnancy in the presence of an autoimmune disease such as vasculitis is often associated with significant morbidity. Little is known about the outcomes when women present with de novo vasculitis during pregnancy, and the appropriate management of such presentations is unclear. We describe a case of a 33-year-old female presenting in her second pregnancy with new onset ANCA vasculitis at 12 weeks' gestation. She was successfully treated with prednisolone and rituximab, and delivered a healthy 2.8 kg boy at 36 weeks' gestation with no clinical manifestations of vasculitis or neutropenia in the neonate.en_US
dc.language.isoeng-
dc.subjectAntineutrophil cytoplasm antibody vasculitisen_US
dc.subjectpregnancyen_US
dc.subjectrituximaben_US
dc.titleA case of ANCA-associated vasculitis presenting de novo in pregnancy, successfully treated with rituximab.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleObstetric Medicineen_US
dc.identifier.affiliationNephrologyen_US
dc.identifier.affiliationDepartment of Obstetric, Medicine, Mercy Health, Melbourne, Australiaen_US
dc.identifier.doi10.1177/1753495X18780853en_US
dc.type.contentTexten_US
dc.identifier.pubmedid32284732-
dc.type.austinJournal Article-
local.name.researcherPaizis, Kathy
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptOlivia Newton-John Cancer Research Institute-
crisitem.author.deptNephrology-
Appears in Collections:Journal articles
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