Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/22306
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dc.contributor.authorWorland, Thomas-
dc.contributor.authorApostolov, Ross-
dc.contributor.authorAsadi, Khashayar-
dc.contributor.authorLeung, Christopher-
dc.date2019-12-28-
dc.date.accessioned2020-01-07T00:33:30Z-
dc.date.available2020-01-07T00:33:30Z-
dc.date.issued2020-06-
dc.identifier.citationLiver International 2020; 40(6): 1500-1502en_US
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/22306-
dc.description.abstractThe recently published manuscript by Zhu and colleagues "Hepatitis B virus infection and risk of non-alcoholic fatty liver disease: A population-based cohort study" found no correlation between presence of chronic HBV and presence of common risk factors for non-alcoholic fatty liver disease on primary analysis. A limitation to this study, like most population based research, is the absence of liver histology, which is considered gold standard for assessment of non-alcoholic fatty liver disease. Our group studied the association between hepatitis B viral activity and non-alcoholic fatty liver disease activity as measured by grade of steatohepatitis/fibrosis on liver biopsy by analysing consecutive liver histology samples from patients with chronic hepatitis B at a single quaternary liver transplant centre. Linear regression modelling for active viral hepatitis on histologic examination against degree of steatohepatitis showed no correlation (r2 0.018, all P>0.1). Linear regression of degree of steatohepatitis versus hepatitis B viral load also showed no correlation. Our work is concordant with the manuscript from Zhu et al; we found no significant correlation between hepatitis B viral activity and degree of steatohepatitis.en_US
dc.language.isoeng-
dc.subjectHepatitis Ben_US
dc.subjectNon-alcoholic fatty liver diseaseen_US
dc.subjectfatty liveren_US
dc.titleHepatitis B virus activity is not associated with degree of liver steatosis in patients with Hepatitis B-related chronic liver disease.en_US
dc.typeJournal Articleen_US
dc.identifier.journaltitleLiver Internationalen_US
dc.identifier.affiliationGastroenterology and Hepatologyen_US
dc.identifier.doi10.1111/liv.14344en_US
dc.type.contentTexten_US
dc.identifier.orcid0000-0001-5122-5750en_US
dc.identifier.pubmedid31883410-
dc.type.austinLetter-
local.name.researcherApostolov, Ross
item.openairetypeJournal Article-
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.grantfulltextnone-
item.fulltextNo Fulltext-
item.cerifentitytypePublications-
item.languageiso639-1en-
crisitem.author.deptGastroenterology and Hepatology-
crisitem.author.deptGastroenterology and Hepatology-
crisitem.author.deptPathology-
crisitem.author.deptGastroenterology and Hepatology-
crisitem.author.deptUniversity of Melbourne Clinical School-
crisitem.author.deptClinical Education-
crisitem.author.deptMedicine (University of Melbourne)-
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