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Title: Quantifying the diagnostic pathway for patients with cognitive impairment: real-world data from Australia.
Authors: Black, Christopher M;Woodward, Michael M;Ambegaonkar, Baishali M;Philips, Alana;Pike, James;Jones, Eddie;Husbands, Joseph;Khandker, Rezaul K
Affiliation: Center for Observational and Real-World Evidence, Merck & Co., Inc., Kenilworth, NJ, USA
Department of Aged Care Services, Austin Health, Heidelberg, Victoria, Australia
MSD, Sydney, NSW, Australia
Adelphi Real World, Macclesfield, UK
Issue Date: 25-Nov-2019
EDate: 2019
Citation: International psychogeriatrics 2019; online first: 25 November
Abstract: Rapid diagnosis of dementia is essential to ensure optimum patient care. This study used real-world data to quantify the dementia diagnostic pathway in Australia. A real-world, cross-sectional survey of physicians and patients. Clinical practice. Primary care or specialist physicians managing patients with cognitive impairment (CI). Descriptive analyses focused on key events in the diagnostic pathway. Regression modeling compared the duration between first consultation and formal diagnosis with various factors. Data for 600 patients were provided by 60 physicians. Mean time from initial symptoms to first consultation was 6.1 ± 4.4 months; 20% of patients had moderate or severe CI at first consultation. Mean time from first consultation to formal diagnosis was 4.0 ± 7.4 months (1.2 ± 3.6 months if not referred to a secondary physician, and 5.3 ± 8.3 months if referred). Time from first consultation to diagnosis was significantly associated with CI severity at first consultation; time was shorter with more severe CI. There was no association of disease severity and referral to a secondary physician; 69.5% of patients were referred, the majority (57.1%) to a geriatrician. The highest proportion of patients were diagnosed by geriatricians (47.4%). Some form of test or scale was used to aid diagnosis in 98.8% of patients. A substantial number of Australians experience cognitive decline and behavioral changes some time before consulting a physician or being diagnosed with dementia. Increasing public awareness of the importance of early diagnosis is essential to improve the proportion of patients receiving comprehensive support prior to disease progression.
DOI: 10.1017/S1041610219001856
PubMed URL: 31762429
Type: Journal Article
Subjects: caregivers
cognitive impairment
early diagnosis
Appears in Collections:Journal articles

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