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|Title:||Novel Target Selection for Nuclear Medicine Studies.|
|Authors:||Lee, Sze Ting;Burvenich, Ingrid J G;Scott, Andrew M|
|Affiliation:||School of Cancer Medicine, La Trobe University, Melbourne, Australia|
Faculty of Medicine, The University of Melbourne, Melbourne, Australia
Department of Molecular Imaging and Therapy, Austin Health, Heidelberg, Victoria, Australia
Olivia Newton-John Cancer Research Institute, Austin Health, Heidelberg, Victoria, Australia
|Citation:||Seminars in nuclear medicine 2019; 49(5): 357-368|
|Abstract:||Nuclear medicine techniques involving SPECT and PET are being increasingly used as a noninvasive tool for the detection, quantitation and therapy response monitoring of a myriad of disease processes through target visualization and kinetic modeling. The target selection requires a good understanding of the physiologic changes involved in the disease processes. The target selected can range from cellular proteins expressed in a particular organ, biochemical pathways in cells, or receptors on circulating blood cells. This can have a significant impact on therapeutic options for subsequent therapies, including radionuclide therapies in this evolving world of theranostic practices, which is outlined in this review.|
|Appears in Collections:||Journal articles|
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