Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/21521
Title: Androgen deficiency in older men.
Authors: Grossmann, Mathis
Affiliation: Department of Medicine, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
Department of Endocrinology, Austin Health, Heidelberg, Victoria, Australia
Issue Date: Jul-2019
Citation: Australian journal of general practice 2019; 48(7): 446-450
Abstract: Older men, especially those who are overweight or obese and have comorbidities, not uncommonly present with non-specific androgen deficiency-like symptoms, such as low energy and sexual dysfunction, and modestly lowered serum testosterone relative to reference ranges based on healthy young men. The aim of this paper is to describe the clinical approach to men who present with non-specific androgen deficiency-like symptoms. Most men who present with non-specific androgen deficiency-like symptoms do not have organic hypogonadism due to pituitary or testicular disease, but instead have functional gonadal axis suppression due to ill health. Lifestyle measures - especially weight loss, optimisation of comorbidities and cessation of offending medications - can improve symptoms and increase serum testosterone; this should be the first-line approach. Recent randomised controlled trials (RCTs) have reported modest benefits of testosterone treatment in stringently selected older men. However, the true long-term risks and benefits of testosterone treatment in such men are not known. Further study is required before testosterone treatment can be routinely recommended for indications other than organic hypogonadism.
URI: http://ahro.austin.org.au/austinjspui/handle/1/21521
ORCID: 0000-0001-8261-3457
PubMed URL: 31256511
Type: Journal Article
Appears in Collections:Journal articles

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