Please use this identifier to cite or link to this item: http://ahro.austin.org.au/austinjspui/handle/1/20192
Title: Pseudomonas meningoencephalitis masquerading as a stroke in a patient on tocilizumab.
Authors: Williams, Cameron J;Foote, Andrew;Choi, Philip
Affiliation: Royal Melbourne Hospital, Parkville, Victoria, Australia
Box Hill Hospital, Box Hill, Victoria, Australia
Austin Health, Heidelberg, Victoria, Australia
Issue Date: 28-Jan-2019
EDate: 2019-01-28
Citation: BMJ case reports 2019; 2019: bcr-2018-227296
Abstract: A previously high-functioning woman presents with clinical and CT features of a subacute ischaemic stroke. Her medical history is relevant for refractory giant cell arteritis on long-term high-dose prednisolone and recent commencement of tocilizumab (interleukin-6 monoclonal antibody). The potential for stroke mimic is considered and a magnetic resonance brain scan is requested. She rapidly deteriorates within 24 hours of admission and unexpectantly dies. An autopsy reveals that she has bilateral pulmonary emboli with lower limb deep vein thrombosis and Pseudomonas meningoencephalitis with frank pus on the brain. We discuss the potential risks of immunosuppression and the role of imaging in the diagnosis of stroke.
URI: http://ahro.austin.org.au/austinjspui/handle/1/20192
DOI: 10.1136/bcr-2018-227296
ORCID: 0000-0003-4952-8896
PubMed URL: 30696642
Type: Journal Article
Subjects: biological agents
neuroimaging
stroke
Appears in Collections:Journal articles

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