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|Title:||Algorithms to facilitate shared decision making for the management of mild-to-moderate ulcerative colitis.|
|Authors:||Jackson, Belinda D;De Cruz, Peter|
|Affiliation:||Department of Gastroenterology, Austin Health, Heidelberg, Victoria, Australia|
Department of Medicine, Austin Health, The University of Melbourne, Heidelberg, Victoria, Australia
|Citation:||Expert review of gastroenterology & hepatology 2018; online first: 4 October|
|Abstract:||Non-adherence has been a key barrier to the efficacy of medical treatments in ulcerative colitis (UC). Engaging patients in their IBD care via shared decision making (SDM) to facilitate self-management may improve adherence to therapy. Areas covered: This review aims to summarize the most recent trial evidence from 2012-2017 for mild-to-moderate UC in order to develop clinical algorithms that guide SDM to facilitate self-management. A structured literature search via multiple electronic databases was performed using the search terms 'ulcerative colitis,' 'treatment,' 'management,' 'medication,' 'maintenance,' 'remission,' '5-ASA,' and 'inflammatory bowel disease. Expert commentary: Novel formulations of existing oral and topical medications have expanded the treatment options available for the induction and maintenance therapy for mild-to-moderate UC. Daily dosing of 5-ASA therapy is equivalent to twice daily dosing. The combination therapies of oral plus topical 5-ASA therapy and 5-ASA plus corticosteroid therapy are more effective than monotherapy. Budesonide MMX now plays a role in the management of mild-to-moderate UC. This review collates the evidence on drug efficacy and safety, adherence and tolerability, and non-invasive monitoring of mild-to-moderate UC into SDM-orientated algorithms to facilitate self-management.|
inflammatory bowel disease
|Appears in Collections:||Journal articles|
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