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|Title:||Beyond penicillin - rapid desensitization for specific flucloxacillin hypersensitivity.|
|Authors:||Kwong, Jason C;Urbancic, Karen F;Trubiano, Jason A|
|Affiliation:||National Centre for Infections in Cancer, Peter MacCallum Cancer Centre, Victoria, Australia|
Department of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia
Pharmacy Department, Austin Health, Heidelberg, Victoria, Australia
Centre for Antibiotic Allergy and Research, Department of Infectious Diseases, Austin Health, Heidelberg, Victoria, Australia
|Citation:||Antimicrobial agents and chemotherapy 2018; online first: 17 September|
|Abstract:||Beta-lactam therapy for severe staphylococcal infections is associated with superior outcomes when compared to non-beta-lactam therapy. In patients with immediate hypersensitivity to beta-lactams, desensitization has been widely employed to allow beta-lactam therapy, but published protocols for anti-staphylococcal beta-lactams such as flucloxacillin are lacking. Here, we report a case and the desensitization protocol successfully used for a patient with isolated flucloxacillin immediate hypersensitivity, where a penicillin desensitization protocol would likely have resulted in an adverse drug reaction.|
|Appears in Collections:||Journal articles|
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