Please use this identifier to cite or link to this item: https://ahro.austin.org.au/austinjspui/handle/1/18743
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dc.contributor.authorGedye, Craig-
dc.contributor.authorCardwell, Tracy-
dc.contributor.authorDimopoulos, Nektaria-
dc.contributor.authorTan, Bee Shin-
dc.contributor.authorJackson, Heather M-
dc.contributor.authorSvobodová, Suzanne-
dc.contributor.authorAnaka, Matthew-
dc.contributor.authorBehren, Andreas-
dc.contributor.authorMaher, Christopher-
dc.contributor.authorHofmann, Oliver-
dc.contributor.authorHide, Winston-
dc.contributor.authorCaballero, Otavia-
dc.contributor.authorDavis, Ian D-
dc.contributor.authorCebon, Jonathan S-
dc.date.accessioned2018-08-30T06:54:45Z-
dc.date.available2018-08-30T06:54:45Z-
dc.date.issued2016-02-
dc.identifier.citationStem cell reviews 2016-02; 12(1): 156-61-
dc.identifier.urihttps://ahro.austin.org.au/austinjspui/handle/1/18743-
dc.description.abstractCancer cell lines can be useful to model cancer stem cells. Infection with Mycoplasma species is an insidious problem in mammalian cell culture. While investigating stem-like properties in early passage melanoma cell lines, we noted poorly reproducible results from an aliquot of a cell line that was later found to be infected with Mycoplasma hyorhinis. Deliberate infection of other early passage melanoma cell lines aliquots induced variable and unpredictable effects on expression of putative cancer stem cell markers, clonogenicity, proliferation and global gene expression. Cell lines established in stem cell media (SCM) were equally susceptible. Mycoplasma status is rarely reported in publications using cultured cells to study the cancer stem cell hypothesis. Our work highlights the importance of surveillance for Mycoplasma infection while using any cultured cells to interrogate tumor heterogeneity.-
dc.language.isoeng-
dc.subjectCancer cell lines, CD133-
dc.subjectCancer stem cells-
dc.subjectMycoplasma-
dc.titleMycoplasma Infection Alters Cancer Stem Cell Properties in Vitro.-
dc.typeJournal Article-
dc.identifier.journaltitleStem cell reviews-
dc.identifier.affiliationDepartment of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, SPH2, 4th Floor, Boston, MA, 02115, USAen
dc.identifier.affiliationSouth African National Bioinformatics Institute, University of the Western Cape, Private Bag X17, Bellville, 7535, South Africaen
dc.identifier.affiliationUniversity of Newcastle, School of Biomedical Sciences and Pharmacy, Hunter Medical Research Institute, New Lambton Heights, NSW, 2305, Australia-
dc.identifier.affiliationWashington University Genome Institute, St. Louis, MO, 63110, USAen
dc.identifier.affiliationLudwig Institute for Cancer Research, Austin Health, Heidelberg, Victoria, Australia-
dc.identifier.affiliationOlivia Newton-John Cancer Research Institute, Heidelberg, Victoria, Australia-
dc.identifier.affiliationLudwig Institute for Cancer Research, New York Branch at Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY, 10021, USA-
dc.identifier.affiliationEastern Health Clinical School, Faculty of Medicine, Nursing and Health Sciences, Monash University, and Eastern Health, Box Hill Hospital, 5 Arnold St, Box Hill, VIC, 3128, Australia-
dc.identifier.affiliationSchool of Cancer Medicine, LaTrobe University, Heidelberg, Victoria, Australia-
dc.identifier.doi10.1007/s12015-015-9630-8-
dc.identifier.orcid0000-0002-1629-4352-
dc.identifier.orcid0000-0001-5329-280Xen
dc.identifier.orcid0000-0002-9066-8244en
dc.identifier.pubmedid26514153-
dc.type.austinJournal Article-
dc.type.austinResearch Support, Non-U.S. Gov't-
local.name.researcherCebon, Jonathan S
item.openairecristypehttp://purl.org/coar/resource_type/c_18cf-
item.cerifentitytypePublications-
item.fulltextNo Fulltext-
item.grantfulltextnone-
item.languageiso639-1en-
item.openairetypeJournal Article-
crisitem.author.deptOlivia Newton-John Cancer Research Institute-
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